viii
A. Bakalova et al./Chemical Papers
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formers of their platinum complexes V, VI. The com-
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toxicity on a SKW-3 and HL-60 human tumour cell
lines. The most significant cytotoxicity was observed
for complex V, which inhibited the viability of cells
tested at low micromolar concentrations and the IC50
value was comparable with that of cisplatin. The new
Pt(II) complexes reported of the general formula cis-
[Pt(NH3)LCl2] V, VI exhibited higher cytotoxic ac-
tivity than the previously studied Pt(II) complexes
with the general formula cis-[PtL2Cl2] VII, VIII and
metal-free ligands III, IV.
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