Studies toward the construction of the allyltrisulfide component in esperamicin-A1 from 5-ketoshikimic acid derivatives: Part 1

Article abstract of DOI:10.1016/S0040-4039(98)02399-5

The conversion of keto ester 1, obtained in either enantiomeric form from (-)-quinic acid, to its corresponding enol silyl ether 4 was examined as the first step to construct the allyl trisulfide unit found in esperamicin A₁. Under different co