Synthesis of α-trifluoromethyl substituted α-amino acid derivatives from methyl 3,3,3-trifluoro-2-diazopropionate

DOI: 10.1016/0040-4039(95)02265-1

Source and publish data:

Tetrahedron Letters p. 615 - 618 (1996)

Update date:2022-08-17

Topics:

Authors:

Osipov, Sergey N.

Sewald, Norbert

Kolomiets, Alexey F.

Fokin, Alexander V.

Burger, Klaus

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Article abstract of DOI:10.1016/0040-4039(95)02265-1

New derivatives 2-7 of α-trifluoromethyl substituted amino acids are synthesized via transformation of ammonium ylides formed on reaction of methyl 3,3,3-trifluoro-2-diazopropionate with amines and amides, respectively.

Full text of DOI:10.1016/0040-4039(95)02265-1

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Product name:METHYL N-[(BENZYLOXY)CARBONYL]-3,3,3-TRIFLUOROALANINATE

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