Synthesis of α-trifluoromethyl substituted α-amino acid derivatives from methyl 3,3,3-trifluoro-2-diazopropionate

Article abstract of DOI:10.1016/0040-4039(95)02265-1

New derivatives 2-7 of α-trifluoromethyl substituted amino acids are synthesized via transformation of ammonium ylides formed on reaction of methyl 3,3,3-trifluoro-2-diazopropionate with amines and amides, respectively.