Journal of the Chemical Society. Perkin transactions I p. 408 - 412 (1981)
Update date:2022-08-11
Topics:
Drewes, Siegfried E.
Pitchford, Andrew T.
Reaction of 2,6-bis(bromomethyl)pyridine with the naturally-occuring C10 necic acid, retronecic acid, results in the formation of a new semi-synthetic cyclic diester alkaloid, pyridine-retronecate.This product is an analogue of a pyrrolizidine alkaloid and retains those characteristics normally held responsible for the toxity of this class of alkaloids.Biological tests carried out on mice injected with retrorsine and with the synthetic analogue suggest that the cytotoxic effects are similar.
View MoreHuaian Double Win Chemicals Co.,Ltd.
Contact:+86-13511538872
Address:Blk 43,Greenland Century Town,Huaian District, Huaian City,Jiangsu Province,China
website:http://www.arromax.com
Contact:+86-0512-62959601 skype:aimmezhang
Address:Suite 401, Bldg A3, 218 Xinghu St.Suzhou Industrial Park 215123, P.R. China
Suzhou Lixin Pharmaceutical Co., Ltd.
Contact:86-512-88169812
Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
VanderArk International Limited
Contact:86-10-82437576
Address:Qing He
Jiangxi Hito Chemical Co., Ltd.
Contact:+86-792-3170318
Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Doi:10.1021/jo00095a050
(1994)Doi:10.1021/jo982030e
(1999)Doi:10.1111/febs.14797
(2019)Doi:10.1039/c39930000860
(1993)Doi:10.1021/es970688o
(1998)Doi:10.1016/j.ica.2011.11.048
(2012)