Synthesis of 9-(2-deoxy-β-D-ribofuranosyl)purine-2-thione

Article abstract of DOI:10.1080/15257770008035029

A synthesis of 9-(2-deoxy-β-D-ribofuranosyl)purine-2-thione was performed by desulfurization of 2'-deoxy-6-thioguanine to give 2-amino-9-(2- deoxy-β-D-ribofuranosyl)purine, diazotization with chloride replacement to give 2-chloro-9-(2-deoxy-β-D-ribofuranosyl)purine, and the replacement of chloride with sulfur using thiolacetic acid and deacetylation.

Full text of DOI:10.1080/15257770008035029

Nucleosides, Nucleotides and Nucleic Acids
ISSN: 1525-7770 (Print) 1532-2335 (Online) Journal homepage: http://www.tandfonline.com/loi/lncn20
Synthesis of 9-(2-Deoxy-β-D-
ribofuranosyl)purine-2-thione
Harry P. Rappaport
To cite this article: Harry P. Rappaport (2000) Synthesis of 9-(2-Deoxy-β-D-
ribofuranosyl)purine-2-thione, Nucleosides, Nucleotides and Nucleic Acids, 19:4, 839-843, DOI:
10.1080/15257770008035029
To link to this article: http://dx.doi.org/10.1080/15257770008035029
Published online: 24 Sep 2006.
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Date: 14 November 2015, At: 03:12