Drastic Effects of Dioxygen on the Selectivity of Reduction by LiAlH4. Milder Conditions Made Possible by Strictly Anaerobic Conditions

Article abstract of DOI:10.1016/0040-4039(95)01291-O

Reduction of the gem-disubstituted cyclopropane 1 with LiAlH4 yields different results under strictly anaerobic conditions and loosely anaerobic ones.Under strictly anaerobic conditions, (+)-1-bromo-2,2-diphenylcyclopropanecarbinol 2 is quantitatively red