Journal of Medicinal Chemistry p. 8656 - 8664 (2013)
Update date:2022-08-16
Topics:
Sahner, J. Henning
Brengel, Christian
Storz, Michael P.
Groh, Matthias
Plaza, Alberto
Müller, Rolf
Hartmann, Rolf W.
The present work deals with the optimization of an inhibitor of PqsD, an enzyme essential for Pseudomonas aeruginosa quorum sensing apparatus. Molecular docking studies, supported by biophysical methods (surface plasmon resonance, isothermal titration cal
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