New compounds: organoboron derivatives of tetracyclines. I. Synthesis of carboxamido derivative of tetracycline with perhydro-2-phenyl-1,3,6,2-dioxazaborocine

Article abstract of DOI:10.1002/jps.2600661047

An organoboron carboxamido derivative of tetracycline, designed for use in the ¹⁰₅B-thermal neutron-capture treatment of cancer, was synthesized under the conditions of the Mannich reaction using perhydro-2-phenyl-1,3,6,2-dioxazaboro