Chemical and Pharmaceutical Bulletin p. 298 - 303 (1998)
Update date:2022-08-30
Topics:
Mimaki, Yoshihiro
Kuroda, Minpei
Kameyama, Aiko
Yokosuka, Akihito
Sashida, Yutaka
Phytochemical examination of the underground parts of Ruscus aculeatus has led to the isolation of a total of twelve steroidal saponins, including seven new ones. The structures of the new saponins were determined by spectroscopic analysis and chemical evidence. The furostanol saponin, having a diglycoside moiety modified with a (2S,3S)-2-hydroxy-3-methylpentanoic acid group and an acetic acid group, and its corresponding spirostanol saponin exhibited cytostatic activity on leukemia HL-60 cells.
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