Three new oxylipids related to 3,6-dioxo-4-docosenoic acid from Okinawan marine sponges, Plakortis spp.

Article abstract of DOI:10.1016/0040-4020(95)00256-8

Manzamenones J (1) and K (2) and plakoridine B (3), three new oxylipins with unique carbon-skeletons related to 3,6-dioxo-4-docosenoic acid, were isolated from Okinawan marine sponges, Plakortis spp., and their structures elucidated on the basis of spectral and chemical means. Absolute stereochemistry of manzamenone A (4) was investigated by applying the modified Mosher's method developed recently for secondary carboxylic acids by Kusumi.