Journal of the American Chemical Society p. 1450 - 1454 (1993)
Update date:2022-08-22
Topics:
Hernández-Laguna
Abboud
Notario
Homan
Smeyers
The gas-phase basicity (GB) of histamine (1) relative to ammonia (defined as the standard Gibbs energy change for reaction 1) has been measured by means of Fourier transform ion cyclotron resonance spectroscopy (FT-ICR): 1H+(g) + NH3(g) ? 1(g) + NH4+(g). The various tautomer/conformers of 1H+(g) were studied by means of ab initio SCF-LCAO-MO calculations at the 6-31G//6-31G level. The calculated proton affinity agrees well with that estimated from FT-ICR results. Ring protonation is slightly preferred over side-chain protonation. Chelation provides a major contribution to the stability of 1H+(g). Comparison of these results with aqueous solution data reveals dramatic differences due to solvation.
View MoreJiaxing Trustworthy Import And Export Co.,Ltd
Contact:+86-573-82030555
Address:Room 1202, Unit B, Charming plaza,No.1558 East Zhongshan Road , Jiaxing City, Zhejiang Province, China.
Wuxi Pharma-Trading Import & Export Co.,Ltd.
Contact:+86-510-82304590 82716390
Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
NINGBO PANGS CHEM INT’L CO., LTD.
Contact:+86-0574-27666801
Address:Floor 21, Building 11, Xintiandi, No. 689, Shijiroad, Ningbo, Zhejiang, China
Hunan Dinuo Pharmaceutical Co.,Ltd.
Contact:86-731-88280100*8561
Address:Bio-pharmaceutical industrial park, Liuyang, Hunan, China
website:http://www.oceanchem-group.com
Contact:86-536-8596048
Address:9th floor,Building B future Plaza, No.88.Fenghuang Street,Weifang,Shandong,China
Doi:10.1055/s-1984-31009
(1984)Doi:10.1021/jo101043m
(2010)Doi:10.1021/jp0012653
(2000)Doi:10.1021/jm00385a032
(1987)Doi:10.1021/jo00180a021
(1984)Doi:10.1002/ejoc.200300332
(2004)