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Benzamide, 2-hydroxy-N-[4-(trifluoromethyl)phenyl]-, also known as 2-Hydroxy-N-[4-(trifluoromethyl)phenyl]benzamide, is a chemical compound with the molecular formula C14H10F3NO2. It is a derivative of benzamide, featuring a hydroxyl group at the 2-position and a trifluoromethyl group at the 4-position of the phenyl ring. Benzamide, 2-hydroxy-N-[4-(trifluoromethyl)phenyl]- is often used in the synthesis of pharmaceuticals and agrochemicals due to its potential biological activity. It is a white crystalline solid with a melting point of approximately 150-152°C. The presence of the trifluoromethyl group can significantly influence the compound's lipophilicity and metabolic stability, which are important factors in drug design.

42043-15-2

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42043-15-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 42043-15-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,2,0,4 and 3 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 42043-15:
(7*4)+(6*2)+(5*0)+(4*4)+(3*3)+(2*1)+(1*5)=72
72 % 10 = 2
So 42043-15-2 is a valid CAS Registry Number.

42043-15-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-N-[4-(trifluoromethyl)phenyl]benzamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

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More Details:42043-15-2 SDS

42043-15-2Downstream Products

42043-15-2Relevant academic research and scientific papers

Novel ZnII complexes of 2-(2-hydroxyphenyl)benzothiazoles ligands: Electroluminescence and application as host materials for phosphorescent organic light-emitting diodes

Wang, Renjie,Deng, Lijun,Fu, Min,Cheng, Jinling,Li, Jiuyan

, p. 23454 - 23460 (2013/03/28)

A group of novel zinc complexes containing 2-hydroxyphenylbenzothiazole (BTZ) ligands were designed and synthesized, in which different substituents (OCH3, CH3, F, CF3, COOCH2CH 3) were attached at th

Analogues of the active metabolite of leflunomide

-

, (2008/06/13)

Analogues of the active metabolite of leflunomide, and to the use thereof as immunosuppressive and/or antinflammatory agents.

A new rational hypothesis for the pharmacophore of the active metabolite of leflunomide, a potent immunosuppressive drug

Bertolini, Giorgio,Aquino, Mario,Biffi, Mauro,D'Atri, Gaetano,Di Pierro, Francesco,Ferrario, Francesco,Mascagni, Paolo,Somenzi, Flavio,Zaliani, Andrea,Leoni, Flavio

, p. 2011 - 2016 (2007/10/03)

Leflunomide is one of the most promising disease-modifying antirheumatic drug now in clinical trials for the treatment of rheumatoid arthritis. Metabolic studies have indicated that leflunomide is rapidly processed in vivo to an active metabolite, A771726

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