
Tetrahedron p. 645 - 649 (1974)
Update date:2022-08-11
Topics:
Cimino
De Rosa
De Stefano
Minale
A new diterpene, isoagatholactone, isolated from the sponge Spongia officinalis, is the first natural compound with the carbon skeleton of isoagathic acid (2), the acid-catalyzed cyclization product of agathic acid (1). Structure 4 was assigned to isoagatholactone on spectral grounds and chemical correlation with grindelic acid (5).
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Doi:10.1016/0021-9517(76)90140-8
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