Catalytic performance of a supramolecular bienzyme complex formed with artificial aminotransferase and natural lactate dehydrogenase

Article abstract of DOI:10.1246/cl.1996.427

A supramolecular bienzyme complex was constituted in a combination of a catalytic bilayer membrane as an artificial aminotransferase with a natural lactate dehydrogenase and the resulting cooperative system enhanced the catalytic activity of the artificial enzyme to promote a sequential transformation of α-amino acids to the corresponding α-hydroxy acids via formation of α-keto acids, exhibiting a marked substrate specificity.