High Resolution NMR Spectroscopic Studies on the Metabolism and Futile Deacetylation of 4-Hydroxyacetanilide (Paracetamol) in the Rat

DOI: 10.1016/0006-2952(95)98513-9

Source and publish data:

Biochemical Pharmacology p. 1155 - 1164 (1995)

Update date:2022-08-11

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Authors:

Nicholls, Andrew W.

Caddick, Stephen

Wilson, Ian D.

Farrant, R. Duncan

Lindos, John C.

Nicholson, Jeremy K.

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Article abstract of DOI:10.1016/0006-2952(95)98513-9

Paracetamol (4-hydroxyacetanilide, acetaminophen) was synthesized with the acetyl group labelled with C²H₃ (paracetamol-C²H₃), and dosed to rats i.p. at 25 mg/kg (N = 5) and 40 mg/kg (N = 3) body weight. Paracet

Full text of DOI:10.1016/0006-2952(95)98513-9

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