
Journal of the Chemical Society. Perkin transactions I p. 967 - 978 (1995)
Update date:2022-08-10
Topics:
Fang, Jim-Min
Lin, Chun-Hung
Bradshaw, Curt W.
Wong, Chi-Huey
This article reviews the use of several oxidoreduction enzymes, including monooxygenases, chloroperoxidase, arene dioxygenase, lipoxygenase, galactose oxidase and alcohol dehydrogenases, in the preparation of optically pure or enriched epoxides, halohydrins, sulfoxides, hydroxyperoxides, alcohols, cyclohexadienediols, lactones and α-hydroxy aldehydes.The mechanisms of some of these enzyme-catalysed transformations, and their scopes and limitations in synthetic chemistry are also discussed.Representative syntheses of a key intermmediate of 5-lipoxygenase inhibitor, a seven-carbon C-glycoside and an active component of the antibiotic bialaphos have been experimentally illustrated using Lactobacillus alcohol dehydrogenase, chloroperoxidase and glutamate dehydrogenase, respectively.
View MoreJintan City Mego Chemical Co., Ltd
Contact:+86-0519-82814387
Address:23# Dengguan Town, Jintan, Jiangsu Province, China
ShangHai Soyoung Biotechnology Inc
website:http://www.soyoungbio.com
Contact:+86-21-69893009
Address:shanghai
Suzhou Tianma Specialty Chemicals Co.,Ltd
Contact:+86-512-68090577
Address:#199, Huayuan Rd, Mudu, Suzhou, Jiangsu, CHINA
Suzhou Kangrun Pharmaceutical, Inc
Contact:86-512-63912376,63913329
Address:Building 2, No. 2358 ,Chang'an Rd, Wujiang Economic Development Zone Pioneering park, china
website:http://www.shochem.com
Contact:021-50800795
Address:No.1043, Halei Rd, Zhangjiang Hi-Tech Park, Shanghai, Postcode 201203, China
Doi:10.1007/BF00604281
(1980)Doi:10.1039/c4ra13395a
(2015)Doi:10.1016/S0040-4039(01)99363-3
(1960)Doi:10.1021/jo50016a007
(1953)Doi:10.1080/00958972.2019.1645329
(2019)Doi:10.1002/aoc.1752
(2011)