Welcome to LookChem.com Sign In|Join Free
  • or


Post Buying Request

78281-72-8 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
Cas No: 78281-72-8
No Data No Data Metric Ton/Day Shanghai Orgpharma Chemical Co., Ltd. Contact Supplier
Cas No: 78281-72-8
No Data 1 Kilogram 10 Metric Ton/Month Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd Contact Supplier
Corey Nepafenac
Cas No: 78281-72-8
USD $ 1.0-1.0 / Kilogram 1 Kilogram 100 Kilogram/Month Career Henan Chemical Co Contact Supplier
Cas No: 78281-72-8
No Data 25 Kilogram 200 Metric Ton/Month Jinan Jianfeng Chemical Co., Ltd Contact Supplier
Lower price Nepafenac
Cas No: 78281-72-8
No Data 1 Gram 100 Gram/Month Qingdao Xinnuo pharmaceutical Chemical Co.,Ltd Contact Supplier
Cas No: 78281-72-8
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Nepafenac CAS 78281-72-8
Cas No: 78281-72-8
USD $ 10.0-10.0 / Gram 10 Gram 100 Metric Ton/Month Hebei yanxi chemical co.,LTD. Contact Supplier
High purity Various Specifications Nepafenac CAS:78281-72-8
Cas No: 78281-72-8
USD $ 100.0-500.0 / Gram 1 Gram 99999 Gram/Year Hangzhou Dingyan Chem Co., Ltd Contact Supplier
Top quality Nepafenac Cas 78281-72-8 with high purity and good service
Cas No: 78281-72-8
USD $ 8.0-10.0 / Gram 100 Gram 30 Kilogram/Month Wuhan Fortuna Chemical Co.,Ltd Contact Supplier
High quality Nepafenac supplier in China
Cas No: 78281-72-8
No Data No Data No Data Simagchem Corporation Contact Supplier

78281-72-8 Usage

Brand name

Nevanac (Alcon).


ChEBI: A monocarboxylic acid amide that is amfenac in which the carboxylic acid group has been converted to the corresponding carboxamide. It is a prodrug for amfenac, used in eye drops to treat pain and inflammation following cataract surgery.


Nepafenac is a non-steroidal anti-inflammatory drug (NSAID), usually sold as a prescription eye drop. It reduces pain and inflammation in the eyes. Nepafenac ophthalmic is used to reduce pain and swelling after cataract surgery. Its side effects may inclu


Labelled Nepafenac (N390080). A non-steroidal anti-inflammatory with analgesic activity; selective COX-2 inhibitor. Prodrug of Amfenac.

Ophthalmic drugs (cataract)

Nepafenac is a novel ophthalmic non-steroidal anti-inflammatory drug (NSAID), for the treatment of eye pain and inflammation caused by cataract surgery, compared with traditional NSAIDs, chemical structure of Nepafenac is conducive to make it rapidly penetrate the cornea and distribute to its target site, which is helpful to reduce the accumulation of the drug in the corneal surface and to reduce the incidence of complications of the eye surface, it has many advantages such as infiltration, targeting strong, little toxic side effects and so on.
August 19, 2005 ,the US Food and Drug Administration (FDA) approved nepafenac ophthalmic suspension for the treatment of cataract surgery-related pain and inflammation, it is the first ophthalmic NSAID prodrug formulation approved for marketing.
Nepafenac after ocular administration, can rapidly pass through the cornea , and under the action of eye tissue hydrolytic enzymes,it can become into ammonia diclofenac (a kind of NSAID); and ammonia diclofenac by inhibiting prostaglandin H synthase ( cyclooxygenase), can block prostaglandin synthesis to play its role as an anti-inflammatory analgesic. As is known, prostaglandin is one of the media causing ocular inflammation it can lead to blood-aqueous barrier crash, vasodilatation, increased vascular permeability and leukocyte chemotaxis, etc. In addition, prostaglandins can also control contraction of the iris sphincter through non-cholinergic mechanism which can trigger the miosis reaction during eye surgery and after surgery. After ocular administration of NSAIDs, it can inhibit prostaglandins synthesis in the iris, ciliary body and conjunctiva, so people can prevent eye inflammation, and reduce the associated pain.
The above information is edited by the chemicalbook of Tian Ye.

Chemical Properties

Light Yellow Solid

78281-72-8 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (SML0288)  Nepafenac  ≥98% (HPLC) 78281-72-8 SML0288-50MG 2,620.80CNY Detail
Sigma (SML0288)  Nepafenac  ≥98% (HPLC) 78281-72-8 SML0288-10MG 644.67CNY Detail
TCI America (N0932)  Nepafenac  >98.0%(HPLC)(T) 78281-72-8 1g 2,990.00CNY Detail
TCI America (N0932)  Nepafenac  >98.0%(HPLC)(T) 78281-72-8 200mg 890.00CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name nepafenac

1.2 Other means of identification

Product number -
Other names 2-Amino-3-benzoylbenzeneacetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:78281-72-8 SDS

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields