Journal of Materials Chemistry B p. 4428 - 4433 (2020)
Update date:2022-08-11
Topics:
Hu, Lianzhe
Hu, Xilu
Huang, Ting
Liao, Hong
Wang, Min
In this study, the phosphatase mimetic activity of zirconium oxide nanoparticles (ZrO2NPs) has been demonstrated. They can effectively catalyze the dephosphorylation of a series of commercial fluorogenic and chromogenic substrates of natural phosphatases. Compared with natural phosphatases, ZrO2NPs possess several advantages such as low cost, facile preparation procedures, and high stability in a broader pH range or at high temperatures. In addition, the activity of ZrO2NPs toward some important biomolecules was investigated. The ZrO2NPs can catalyze the dephosphorylation of ATP ando-phospho-l-tyrosine, but they cannot react with DNA strands. These data are important for the further bio-related applications of ZrO2NPs. Finally, the potential application of ZrO2NPs in intracellular imaging is also demonstrated by using a near-infrared fluorescent substrate of alkaline phosphatase.
View MoreLonzeal Pharmaceuticals Co., Ltd.
website:http://www.lonzeal.com
Contact:+86-13381011962
Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
Shandong Wanda Organosilicon New Material Co., Ltd
Contact:+86-21-54177116;54302881
Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Jurong Huaheng Natural Biological Products Factory
website:http://www.risebiochem.com
Contact:+86-13921007726
Address:Chuncheng town,Jurong city,Jiangsu province,China
Shaanxi King Stone Enterprise Company Limited
Contact:86-29-88353805,13609285751
Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Hangzhou Yanshan Chemical Co.,Ltd.
Contact:86-571- 87698076
Address:Room 1001, #1 Building, Zhongtian MCC, No.2 Youzhinong, Wenyi West Road, Xihu District, Hangzhou, China
Doi:10.1246/bcsj.79.1711
(2006)Doi:10.1246/bcsj.60.794
(1987)Doi:10.1007/BF00666248
(1988)Doi:10.1016/j.jallcom.2008.11.123
(2009)Doi:10.1002/chem.200305562
(2004)Doi:10.1139/v56-187
(1956)