79388-07-1

Basic information

• Product Name: 1,6-diamino-4-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile
• Synonyms: 1,6-diamino-4-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile
• CAS NO: 79388-07-1
• Molecular Weight: 281.274
• Mol File: 79388-07-1.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 1,6-diamino-4-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-diamino-4-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile(79388-07-1)
• EPA Substance Registry System: 1,6-diamino-4-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile(79388-07-1)

Safety Data

• Hazardous Substances Data: 79388-07-1(Hazardous Substances Data)

Upstream product

• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 123-11-5 4-methoxy-benzaldehyde 
• 140-87-4 Cyanoacetohydrazide 
• 109-77-3 malononitrile 
• 105-56-6 ethyl 2-cyanoacetate 
• 85046-00-0 Cyanessigsaeure-(4-methoxybenzyliden)-hydrazid 

Downstream Products

• 1423626-02-1 2-(1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-3-[(4-oxo-4H-chromen-3-yl)methylidene]-9-(4-methoxyphenyl)-4,7-dioxo-4,5,6,7-tetrahydropyrido[1,2-b][1,2,4]triazepine-8,10-dicarbonitrile 

Relevant articles and documents

A three component one-pot synthesis of N-amino-2-pyridone derivatives catalyzed by KF-Al2O3

Synthesis of 1,6-diamino-4-phenyl-3,5-dicyano-2-pyridone derivatives via a one-pot, three-component reaction of aryl aldehydes, malononitrile, and cyanoacetic hydrazide at room temperature using KF-Al2O3 as a recyclable catalyst have been developed. The reaction proceeds through the initial Knoevenagel condensation between aldehyde and malononitrile in the presence of KF-Al2O3 to form the benzylidene derivative which then undergoes Michael addition with cyanoacetic hydrazide followed by intramolecular cyclization of the resulting intermediate to produce the N-amino-2-pyridones in good to excellent yields. The structure of the synthesized compounds were characterized and established on the basis of their spectral data analysis and single-crystal XRD analysis.

1,6-Diamino-2-oxopyridine-3,5-dicarbonitrile Derivatives in the Mannich Reaction

Abstract: 1,6-Diamino-2-oxo-1,2,3,4-tetrahydropyridine-3,5-dicarbonitriles under the action of primary aliphatic amines and an excess of 37% formalin in ethanol were converted into 2,3,8,9-tetrahydro-6,10-methano[1,2,4]triazolo[1,5-a][1,5]diazocine-6,10(7

Nano-Co3S4 as a Retrievable and Robust Catalyst for the Synthesis of 2-Oxo-pyridines and 5-Oxo-[1,2,4]triazolo[2,3-a]pyridines

-

Dipyrido[1,2-b:3′,4′-e][1,2,4]triazine Scaffolds from Pentafluoropyridine

Annelation reaction between pentafluoropyridine and diaminodihydro substituted pyridine derivatives gave dipyrido[1,2-b:3′,4′-e][1,2,4]triazine systems as major products arising from the initial nucleophilic substitution of more nucleophilic N-amino group