Asymmetric synthesis of (1R,2S,3R)-2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole

DOI: 10.1016/0040-4039(95)01155-b

Source and publish data:

Tetrahedron Letters p. 5969 - 5972 (1995)

Update date:2022-08-11

Topics:

Authors:

Cliff Cliff

Pyne Pyne

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Article abstract of DOI:10.1016/0040-4039(95)01155-b

A method for preparing the biologically active compound (1R,2S,3R)-2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole 1 using a palladium (0) catalysed coupling of 1-ethoxymethyl-4-iodomidazole 2 to the functionalised vinylstannane 3 and the Sharpless catalytic asymmetric dihydroxylation is reported.

Full text of DOI:10.1016/0040-4039(95)01155-b

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