Synlett p. 73 - 76 (2019)
Update date:2022-08-10
Topics:
Chen, Xing-Guo
Wu, Qiu-Li
Hou, Fei
Wang, Xi-Cun
Quan, Zheng-Jun
An effective method for the P-alkylation of N -arylphosphinecarboxamides was demonstrated. Primary N -arylphosphinecarboxamides without additional protection underwent P-monoalkylation with various alkyl halides in the presence of cesium carbonate as a promoter. The reactivity of phosphinecarboxamides was also explored.
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