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Name	Furethidine	EINECS	N/A
CAS No.	2385-81-1	Density	1.093g/cm³
PSA	48.00000	LogP	2.71680
Solubility	N/A	Melting Point	~28°
Formula	C21H31 N O4	Boiling Point	470.3°Cat760mmHg
Molecular Weight	361.481	Flash Point	238.2°C
Transport Information	N/A	Appearance	N/A
Safety	Poison by ingestion, subcutaneous, and intravenous routes. When heated to decomposition it emits toxic fumes of NO_x. Can be habit forming. This is a controlled substance (opiate) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.11 (1985). When heated to decomposition it emits toxic fumes of NO_x. See also ESTERS.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	Isonipecoticacid, 4-phenyl-1-[2-[(tetrahydrofurfuryl)oxy]ethyl]-, ethyl ester(6CI,7CI,8CI); Furethidine

Furethidine Chemical Properties

IUPAC Name: [ Ethyl 1-[2-(oxolan-2-ylmethoxy)ethyl]-4-phenylpiperidine-4-carboxylate
Synonyms of Furethidine (CAS NO.2385-81-1) : Ethyl 4-phenyl-1-(2-tetrahydrofurfuryloxyethyl)piperidine-4-carboxylate ; Furethidine ; Furethidinum ; Furetidina ; 1-(2-Tetrahydrofurfuryloxyethyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester ; Isonipecotic acid, 4-phenyl-1-(2-((tetrahydrofurfuryl)oxy)ethyl)-, ethyl ester
InChI: InChI=1/C21H31NO4/c1-2-25-20(23)21(18-7-4-3-5-8-18)10-12-22(13-11-21)14-16-24-17-19-9-6-15-26-19/h3-5,7-8,19H,2,6,9-17H2,1H3
CAS NO:2385-81-1
Molecular Formula:C₂₁H₃₁NO₄
Molecular Weight :361.4751
Molecular Structure :
EINECS: 219-195-0
Index of Refraction:1.519
Surface Tension: 40.2 dyne/cm
Density: 1.093 g/cm³
Flash Point: 238.2 °C
Enthalpy of Vaporization: 73.29 kJ/mol
Boiling Point: 470.3 °C at 760 mmHg
Vapour Pressure: 5.11E-09 mmHg at 25°C

Furethidine Uses

Furethidine (CAS NO.2385-81-1) is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.

Furethidine Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	15500ug/kg (15.5mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	British Journal of Pharmacology and Chemotherapy. Vol. 15, Pg. 254, 1960.
rat	LD50	oral	135mg/kg (135mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	British Journal of Pharmacology and Chemotherapy. Vol. 15, Pg. 254, 1960.
rat	LD50	subcutaneous	26mg/kg (26mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	British Journal of Pharmacology and Chemotherapy. Vol. 15, Pg. 254, 1960.

Furethidine Safety Profile

Poison by ingestion, subcutaneous, and intravenous routes. When Furethidine (CAS NO.2385-81-1) is heated to decomposition, it emits toxic fumes of NO_x. Can be habit forming. This is a controlled substance (opiate) listed in the U.S. Code of Federal Regulations, Title 21 Part 1308.11 (1985). When heated to decomposition it emits toxic fumes of NO_x. See also ESTERS.