- Haloperidol
- Haloperidol decanoate
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| Name |
Haloperidol decanoate |
EINECS | 277-679-7 |
| CAS No. | 74050-97-8 | Density | 1.14 g/cm3 |
| PSA | 46.61000 | LogP | 8.05510 |
| Solubility | N/A | Melting Point |
326.1 °C |
| Formula | C31H41ClFNO3 | Boiling Point | 615.5 °C at 760 mmHg |
| Molecular Weight | 530.123 | Flash Point | 326.1°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Haldoldecanoate;Halomonth;KD 136;KD 16;Neoperidole;R13762; |
Haloperidol decanoate Chemical Properties
Molecular structure of Haloperidol decanoate (CAS NO.74050-97-8) is:
Product Name: Haloperidol decanoate
CAS Registry Number: 74050-97-8
IUPAC Name: [4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl]decanoate
Molecular Weight: 530.113543 [g/mol]
Molecular Formula: C31H41ClFNO3
XLogP3: 7.9
H-Bond Donor: 0
H-Bond Acceptor: 5
EINECS: 277-679-7
Surface Tension: 46.6 dyne/cm
Density: 1.14 g/cm3
Flash Point: 326.1 °C
Enthalpy of Vaporization: 91.32 kJ/mol
Boiling Point: 615.5 °C at 760 mmHg
Vapour Pressure: 4.38E-15 mmHg at 25 °C
Product Categories: Organics
Haloperidol decanoate Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intramuscular | > 1gm/kg (1000mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| mouse | LD50 | intramuscular | > 3500mg/kg (3500mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| mouse | LD50 | intraperitoneal | 288mg/kg (288mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| mouse | LD50 | oral | 739mg/kg (739mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| mouse | LD50 | subcutaneous | 1990mg/kg (1990mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| rat | LD50 | intramuscular | > 1525mg/kg (1525mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| rat | LD50 | intraperitoneal | 328mg/kg (328mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| rat | LD50 | oral | 1717mg/kg (1717mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| rat | LD50 | subcutaneous | 780mg/kg (780mg/kg) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985. |
| women | TDLo | intravenous | 11600ug/kg/4D (11.6mg/kg) | CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE CARDIAC: CHANGE IN RATE | Annals of Internal Medicine. Vol. 119, Pg. 391, 1993. |
Haloperidol decanoate Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion, subcutaneous, and intramuscular routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: arrhythmias, EKG changes, heart rate changes. When heated to decomposition it emits toxic fumes of F−, Cl−, and NOx.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III
Haloperidol decanoate Specification
Haloperidol decanoate , its cas register number is 74050-97-8. It also can be called Haloperidol decanoate [USAN:BAN:JAN] ; Decanoic acid, 4-(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester ; Decanoic acid, ester with 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone ; Depot haloperidol ; Haldol ; Haldol decanoas ; Haldol decanoate ; Halomonth ; Haloperidol decanoate ; Haloperidol depot .
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