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Helveticoside

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Name

Helveticoside

EINECS N/A
CAS No. 630-64-8 Density 1.36±0.1 g/cm3 (20 ºC 760 Torr)
PSA 142.75000 LogP 1.77920
Solubility N/A Melting Point 170°C (dec.)
Formula C29H42 O9 Boiling Point 735.611°C at 760 mmHg
Molecular Weight 534.647 Flash Point 240.263°C
Transport Information N/A Appearance N/A
Safety Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes. Risk Codes R26/27/28
Molecular Structure Molecular Structure of 630-64-8 (ALLEOSIDE A) Hazard Symbols T+
Synonyms

Erysimotoxin(6CI,7CI); Helveticoside (8CI); Deglucoerysimoside; Erysimin; Strophanthidin 3b-digitoxoside; Strophanthidindigitoxoside

 

Helveticoside Chemical Properties

IUPAC Name: (3S,5S,8R,9S,10S,13R,14S,17R)-3-[(2R,4S,5S,6R)-4,5-Dihydroxy-6-methyloxan-2-yl]oxy-5,14-dihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
CAS: 630-64-8
Molecular Formula C29H42O9
Molecular Weight 534.63838
The Molecular Structure of Helveticoside (CAS NO.630-64-8 ):

Density: 1.36 g/cm3 
Flash Point: 240.3 °C
Melting Point: 170°C (dec.)
Boiling Point: 735.6 °C at 760 mmHg 
Index of Refraction: 1.609 
Molar Refractivity: 135.44 cm3 
Molar Volume: 390.9 cm3 
Polarizability: 53.69×10-24cm3 
Surface Tension: 65.1 dyne/cm  
Enthalpy of Vaporization: 122.53 kJ/mol 
Vapour Pressure: 5.59E-25 mmHg at 25°C

Helveticoside Toxicity Data With Reference

1.    

ivn-rat LD50:54 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 155 (1965),165.
2.    

ipr-mus LD50:7800 µg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 155 (1965),165.
3.    

ivn-cat LDLo:50 µg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 155 (1965),165.

Helveticoside Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits acrid smoke and fumes.
Safety Information about Helveticoside ( CAS NO.630-64-8 ):
Hazard Codes: 
T+: Very
Risk Statements: 
R26/27/28: Very Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 
S22: Do not breathe dust.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
RIDADR: 3249
RTECS: FH4919830
HazardClass: 6.1(b)
PackingGroup: III

Helveticoside Specification

  Helveticoside with CAS number of 630-64-8 is also known as Card-20(22)-enolide,3-((2,6-dideoxy-beta-d-ribo-hexopyranosyl)oxy)-5,14-dihydr ; Deglucoerysimoside ; Erizimin ; Erysimotoxin ; Helvetikosid ; Helveticoside ; Helveticoside hydrate ; Erysimin . This product shoud be storaged at 2-8°C.

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