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KN 62

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KN 62

EINECS
CAS No. 127191-97-3 Density 1.388 g/cm3
Solubility Melting Point 92-94 °C
Formula C38H35N5O6S2 Boiling Point 964.731 °C at 760 mmHg
Molecular Weight 721.84 Flash Point 537.25 °C
Transport Information Appearance Yellow solid
Safety 24/25 Risk Codes
Molecular Structure Molecular Structure of 127191-97-3 (KN 62) Hazard Symbols
Synonyms

5-Isoquinolinesulfonicacid,4-[2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenylester, (S)-;5-Isoquinolinesulfonicacid,4-[(2S)-2-[(5-isoquinolinylsulfonyl)methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)propyl]phenylester;

 

KN 62 Chemical Properties

 
IUPAC Name: [4-[(2S)-2-[isoquinolin-5-ylsulfonyl(methyl)amino]-3-oxo-3-(4-phenylpiperazin-1-yl)propyl]phenyl] isoquinoline-5-sulfonate
Empirical Formula: C38H35N5O6S2
Molecular Weight: 721.8444
Product Categories: Protein Kinase Inhibitors and Activators; Protein Kinase
Classification Code: Enzyme inhibitors; Protein Kinase Inhibitors
Melting Point: 92-94 °C
storage temp.: -20 °C
solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.93 mg/mL
form: solid
color: white
Index of Refraction: 1.685
Molar Refractivity: 197.71 cm3
Molar Volume: 519.8 cm3
Surface Tension: 65.1 dyne/cm
Density: 1.388 g/cm3
Flash Point: 537.2 °C
Enthalpy of Vaporization: 140.66 kJ/mol
Boiling Point: 964.7 °C at 760 mmHg
Vapour Pressure of KN-62 (CAS NO.127191-97-3): 0 mmHg at 25 °C

KN 62 Uses

  KN-62 (CAS NO.127191-97-3)is used as a specific inhibitor of Ca2+/Calmodulin-dependent protein kinase II.

KN 62 Safety Profile

Safety Statements: 24/25 
S24/25:Avoid contact with skin and eyes.
WGK Germany of KN-62 (CAS NO.127191-97-3): 3

KN 62 Specification

  KN-62 (CAS NO.127191-97-3), its Synonyms are 1-(N,O-Bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl)-4-phenylpiperazine ; 5-Isoquinolinesulfonic acid, 4-(2-((5-isoquinolinylsulfonyl)methylamino)-3-oxo-3-(4-phenyl-1-piperazinyl)propyl)phenyl ester, (S)- ; KN62 .

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