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Lidofenin

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Name

Lidofenin

EINECS 261-636-4
CAS No. 59160-29-1 Density 1.352 g/cm3
PSA 106.94000 LogP 0.78610
Solubility N/A Melting Point 210 °C (dec.)(lit.)
Formula C14H18 N2 O5 Boiling Point 546.3 °C at 760 mmHg
Molecular Weight 294.307 Flash Point 284.2 °C
Transport Information N/A Appearance white crystalline powder
Safety Poison by intravenous route. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx. Risk Codes 36/37/38
Molecular Structure Molecular Structure of 59160-29-1 (N-(2,6-DIMETHYLPHENYLCARBAMOYLMETHYL)IMINODIACETIC ACID) Hazard Symbols IrritantXi
Synonyms

HIDA;Lidofenin;N-(2,6-Dimethylacetanilide)iminodiacetic acid;N-(2,6-Dimethylphenylcarbamoylmethyl)iminodiacetic acid;

Article Data 4

Lidofenin Chemical Properties

Molecular Structure of Lidofenin (CAS NO.59160-29-1):

IUPAC Name: 2-[carboxymethyl-[2-(2,6-dimethylanilino)-2-oxoethyl]amino]acetic acid
Empirical Formula: C14H18N2O
Molecular Weight: 294.3031 
Index of Refraction: 1.611 
Surface Tension: 63.6 dyne/cm 
Density: 1.352 g/cm
Flash Point: 284.2 °C 
Enthalpy of Vaporization: 86.86 kJ/mol 
Boiling Point: 546.3 °C at 760 mmHg 
Vapour Pressure: 9.05E-13 mmHg at 25°C  
Chemical Properties : white crystalline powder
Product Categories: Analytical Chemistry;Ligands for Pharmaceutical Research ; Radiopharmaceutical Chemistry (Chelating Reagents)
Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Strong oxidants.
Hazardous Decomposition Products Irritating and toxic fumes and gases.
Hazardous Polymerization Hazardous Polymerization
Synonyms of Lidofenin (CAS NO.59160-29-1): N-(2,6-dimethylphenylcarbamoylmethyl)iminodiacetic acid;n-(2,6-xylidinocarbonylmethyl)iminodiacetic acid ; (((2,6-xylylcarbamoyl)methyl)imino)di-aceticaci ; 2,2’-(n-(2,6-dimethylphenylcarbamoylmethyl)imino)di-aceticac i; hida ; lidofenin ; n-(2,6-dimethyl-phenyl-carbamoylmethyl)-iminodiaceticaci ; n-(carboxymethyl)-n-(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)-glycin

Lidofenin Production

Raw materials :Sodium hydroxide-->Ethyl acetate-->Acetic anhydride-->Azabenzene-->2,6-Dimethylaniline-->Nitrilotriacetic acid

Lidofenin Toxicity Data With Reference

1.    

ivn-rat LD50:88 mg/kg

    YACHDS    Yakuri to Chiryo. Pharmacology and Therapeutics. 6 (1978),1331.
2.    

ipr-mus LD50:1100 mg/kg

    EJNMD9    European Journal of Nuclear Medicine. 3 (1978),41.
3.    

ivn-mus LD50:168 mg/kg

    DRFUD4    Drugs of the Future. 4 (1979),342.

Lidofenin Consensus Reports

Reported in EPA TSCA Inventory.

Lidofenin Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes IrritantXi
Risk Statements 36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
 

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