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| CAS No.: | 84994-24-1 |
|---|---|
| Name: | MAEM |
| Molecular Structure: | |
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| Formula: | C13H10 N4 O3 S2 |
| Molecular Weight: | 350.44 |
| Synonyms: | 4-Thiazoleaceticacid, 2-amino-a-(methoxyimino)-,2-benzothiazolyl ester, (Z)-;(Z)-2-[Methoxyimino]-2-(2-aminothiazol-4-yl)acetic acid;(Z)-2-[Methoxyimino]-2-(2-aminothiazol-4-yl)acetic acid 2-benzothiazole ester |
| EINECS: | 279-540-6 |
| Density: | 1.63g/cm3 |
| Boiling Point: | 563.2°C at 760 mmHg |
| Flash Point: | 294.4°C |
| Hazard Symbols: | R36/37/38:; |
| Risk Codes: | Xi:Irritant; "> |
| PSA: | 171.19000 |
| LogP: | 3.67310 |

2-methoxyimino-2-(2-aminothiazol-4-yl)acetic acid S-2-benzothiazole ester


cefteram

| Conditions | Yield |
|---|---|
| With sodium metabisulfite; triethylamine In methanol; dichloromethane at 0℃; for 3h; | 89.1% |


2-methoxyimino-2-(2-aminothiazol-4-yl)acetic acid S-2-benzothiazole ester

A

7-<(Z)-2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido>-3(Z)-(4-methylthiazol-5-yl)vinyl-3-cephem-4-carboxylic acid sodium salt

B

7-<(Z)-2-(2-Aminothiazol-4-yl)-2-methoxyiminoacetamido>-3(E)-(4-methylthiazol-5-yl)vinyl-3-cephem-4-carboxylic acid sodium salt

| Conditions | Yield |
|---|---|
| Stage #1: 7-amino-3-[2-(4-methyl-5-thiazolyl)vinyl]-3-cephem-4-carboxylic acid; 7-amino-3-[(E)-2-(4-methyl-5-thiazolyl)vinyl]-3-cephem-4-carboxylic acid; 2-methoxyimino-2-(2-aminothiazol-4-yl)acetic acid S-2-benzothiazole ester With triethylamine In water; acetone at 0 - 15℃; for 3 - 4h; Stage #2: With sodium 2-ethylhexanoic acid In water; acetone at 20 - 25℃; for 1h; Product distribution / selectivity; |

Product Name: Maem
Synonyms : Benzothiazol-2-yl (Z)-2-methoxyimino-2-(2-aminothiazole-4-yl)thioacetate
Molecular Structure of Maem (CAS NO. 84994-24-1) : 
Molecular Formula of Maem (CAS NO. 84994-24-1) : C13H10N4O2S3
Molecular Weight of Maem (CAS NO. 84994-24-1) : 350.44
CAS NO: 84994-24-1
Product Categories: Amines;Cefotaxime;Ceftriaxone
Mol File: 84994-24-1.mol
Appearance: Maem (CAS NO. 84994-24-1) is white or light yellow crystalline powder.
Maem (CAS NO. 84994-24-1) is intermediates of Cephalosporins antibiotics drugs , and raw materials in the production of ceftriaxone, cefotaxime sodium and other drug.
Maem (CAS NO. 84994-24-1) can be obtained ,with AT, M as raw materials and cyclohexyl carbodiimide and pyridine as the catalyst.