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Cas Database

Name	METHOXYCHLOR	EINECS	200-779-9
CAS No.	72-43-5	Density	1.4 g/cm3
PSA	18.46000	LogP	5.20590
Solubility	In water, 0.1 mg/l @ 25 deg C	Melting Point	86-88 °C(lit.)
Formula	C16H15 Cl3 O2	Boiling Point	greater than or equal to 100 °C.
Molecular Weight	345.653	Flash Point	less than 60 degrees C
Transport Information	N/A	Appearance	COLOURLESS TO LIGHT YELLOW CRYSTALS , WITH CHARACTERISTIC ODOUR.
Safety	Suspected carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Moderately toxic by intraperitoneal and skin contact routes. Human systemic effects by skin contact: somnolence. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits highly toxic fumes of Cl⁻. See also DDT and CHLOROPHENOLS.	Risk Codes	20/21/22-40
Molecular Structure		Hazard Symbols	Toxic material. TLV: TWA 10 mg/m³; not classifiable as a human carcinogen.
Synonyms	Ethane,1,1,1-trichloro-2,2-bis(p-methoxyphenyl)- (8CI);1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane;1,1,1-Trichloro-2,2-bis(p-methoxyphenyl)ethane;1,1,1-Trichloro-2,2-di(4-methoxyphenyl)ethane;1,1-Bis(p-methoxyphenyl)-2,2,2-trichloroethane;2,2,2-Trichloro-1,1-bis(4-methoxyphenyl)ethane;2,2-Bis(4-methoxyphenyl)-1,1,1-trichloroethane; 2,2-Bis(p-methoxyphenyl)-1,1,1-trichloroethane;2,2-Di-p-anisyl-1,1,1-trichloroethane;4,4'-(2,2,2-Trichloroethylidene)dianisole; DMDT;Di(p-methoxyphenyl)(trichloromethyl)methane; Dimethoxy-DDT; Marlate; Mesox K;Methoxcide; Methoxy-DDT; Methoxychlor; Metox; Metox plynny; Mezox K; NSC 8945;p,p'-DMDT; p,p'-Dimethoxydiphenyltrichloroethane; p,p'-Methoxychlor	Article Data	20

METHOXYCHLOR Chemical Properties

Other names:Methoxcide,Dimethoxy-DDT,Methoxy-DDT
Molecular formula:C₁₆H₁₅Cl₃O₂
Molar mass:345.65 g mol-1
Melting point:87 °C, 360 K, 189 °F
Boiling point:decomposes

METHOXYCHLOR Uses

Methoxychlor is a synthetic organochlorine used as an insecticide.

METHOXYCHLOR Toxicity Data With Reference

1.	spm-rat-orl 28 g/kg/10W-C	PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 176 (1984),187.
2.	cyt-ham-ipr 50 mg/kg	ARTODN Archives of Toxicology. 58 (1985),152.
3.	orl-rat TDLo:18,200 mg/kg/2Y-C:CAR,TER	EVHPAZ EHP, Environmental Health Perspectives. Subseries of DHEW Publications. 36 (1980),205.
4.	orl-mus TDLo:56,700 mg/kg/90W-C:CAR,TER	JCROD7 Journal of Cancer Research and Clinical Oncology. 93 (1979),173.
5.	orl-rat TD:80 g/kg/2Y-C:CAR,TER	LIFSAK Life Sciences. 24 (1979),1367.
6.	orl-rat TD:72,800 mg/kg/2Y-C:CAR	EVHPAZ EHP, Environmental Health Perspectives. Subseries of DHEW Publications. 36 (1980),205.
7.	orl-hmn LDLo:6430 mg/kg	PCOC** Pesticide Chemicals Official Compendium ,Association of the American Pesticide Control Officials, Inc.(Topeka, KS.: )1966,705.
8.	skn-hmn TDLo:2414 mg/kg:CNS	PCOC** Pesticide Chemicals Official Compendium ,Association of the American Pesticide Control Officials, Inc.(Topeka, KS.: )1966,705.
9.	orl-rat LD50:5000 mg/kg	JPETAB Journal of Pharmacology and Experimental Therapeutics. 99 (1950),140.
10.

METHOXYCHLOR Consensus Reports

IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal No Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 ,1979,p. 259.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 5 ,1974,p. 193.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-35 ,1978. . EPA Genetic Toxicology Program. Community Right-To-Know List.

METHOXYCHLOR Safety Profile

Suspected carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Moderately toxic by intraperitoneal and skin contact routes. Human systemic effects by skin contact: somnolence. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits highly toxic fumes of Cl⁻. See also DDT and CHLOROPHENOLS.

METHOXYCHLOR Standards and Recommendations

OSHA PEL: TWA Total Dust: 10 mg/m³; 5 mg/m³
ACGIH TLV: TWA 10 mg/m³; Not Classifiable as a Human Carcinogen
DFG MAK: 15 mg/m³

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