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Mazaticol hydrochloride

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Name

Mazaticol hydrochloride

EINECS N/A
CAS No. 32891-29-5 Density g/cm3
PSA 106.25000 LogP 4.98000
Solubility N/A Melting Point N/A
Formula C21H27 N O3 S2 . Cl H Boiling Point 528.7°Cat760mmHg
Molecular Weight 442.07 Flash Point 273.5°C
Transport Information N/A Appearance N/A
Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx, NOx, and HCl. See also ESTERS. Risk Codes N/A
Molecular Structure Molecular Structure of 32891-29-5 (PG 501) Hazard Symbols N/A
Synonyms

Glycolic acid, di-2-thienyl-,6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester hydrochloride, exo- (8CI);9-Azabicyclo[3.3.1]nonane, 2-thiopheneacetic acid deriv.;KAO 264;Mazaticolhydrochloride;PG 501;

 

Mazaticol hydrochloride Chemical Properties

The IUPAC name of Mazaticol hydrochloride (CAS NO.32891-29-5): (8,8,9-Trimethyl-9-azabicyclo[3.3.1]nonan-3-yl) 2-hydroxy-2,2-dithiophen-2-ylacetate hydrochloride 
Synonyms: 6,6,9-Trimethyl-9-azabicyclo(3,3,1)non-3beta-yl alpha,alpha-di(2-thienyl)glycolate hydrochloride ; Glycolic acid, di-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo(3.3.1)non-3-yl ester, hydrochloride, exo- ; Mazaticol HCl ; Mazaticol hydrochloride
CAS: 32891-29-5 
Molecular Weight: 442.03492 g/mol
Molecular Formula: C21H28ClNO3S2 
Molecular Structure:

Flash Point: 273.5 °C 
Boiling Point: 528.7 °C at 760 mmHg

Mazaticol hydrochloride Toxicity Data With Reference

The toxicity of Mazaticol hydrochloride (CAS NO.32891-29-5):

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 126mg/kg (126mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 2448, 1972.
mouse LD50 intravenous 20200ug/kg (20.2mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 2448, 1972.
mouse LD50 oral 263mg/kg (263mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 67, Pg. 387, 1971.
mouse LD50 subcutaneous 341mg/kg (341mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 2448, 1972.
rat LD50 intraperitoneal 104mg/kg (104mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 2448, 1972.
rat LD50 intravenous 12900ug/kg (12.9mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 67, Pg. 387, 1971.
rat LD50 oral 1182mg/kg (1182mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 2448, 1972.
rat LD50 subcutaneous > 1099mg/kg (1099mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE Kiso to Rinsho. Clinical Report. Vol. 6, Pg. 2448, 1972.

Mazaticol hydrochloride Safety Profile

The safety information of Mazaticol hydrochloride (CAS NO.32891-29-5):
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx, NOx, and HCl. See also ESTERS.

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