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Cas Database |
| Name |
Mebutamate |
EINECS | N/A |
| CAS No. | 64-55-1 | Density | 1.114g/cm3 |
| PSA | N/A | LogP | N/A |
| Solubility | N/A | Melting Point |
77-79° |
| Formula | C10H20 N2 O4 | Boiling Point | 435°C at 760 mmHg |
| Molecular Weight | 232.28 | Flash Point | 216.8°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion. Moderately toxic by intraperitoneal route. An FDA proprietary drug. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
1,3-Propanediol,2-methyl-2-(1-methylpropyl)-, dicarbamate (9CI); 1,3-Propanediol, 2-sec-butyl-2-methyl-,dicarbamate (8CI); Carbamic acid, 2-sec-butyl-2-methyltrimethylene ester (6CI);2,2-Dicarbamyloxymethyl-3-methylpentane; 2-sec-Butyl-2-methyl-1,3-propanediyldicarbamate; 2-sec-Butyl-2-methyltrimethylene dicarbamate; Axiten; Butatensin;Capla; Carbuten; Dicamoylmethane; Dormate; Encapla; Ipotensivo; Mebutamat;Mebutamate; Mebutina; Mega; Mioartrina; NSC 163921; No-Press; Prean; Preminex;Sigmafon; Vallene; W 583 |
Article Data | 6 |
Mebutamate Chemical Properties
Molecular Structure of Mebutamate (CAS NO.64-55-1):
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IUPAC Name: [2-(carbamoyloxymethyl)-2,3-dimethylpentyl] carbamate
Empirical Formula: C10H20N2O4
Molecular Weight: 232.2768
Surface Tension: 41.8 dyne/cm
Density: 1.114 g/cm3
Flash Point: 216.8 °C
Enthalpy of Vaporization: 69.12 kJ/mol
Boiling Point: 435 °C at 760 mmHg
Vapour Pressure: 9.09E-08 mmHg at 25°C
Index of Refraction: 1.477
Classification Code: Antihypertensive; Drug / Therapeutic Agent
Synonyms of Mebutamate (CAS NO.64-55-1): 1,3-Propanediol, 2-methyl-2-(1-methylpropyl)-, dicarbamate;1,3-Propanediol, 2-sec-butyl-2-methyl-, dicarbamate ; 2,2-Dicarbamyloxymethyl-3-methylpentane;2-Methyl-2-sec-butyl-1,3-propanediol dicarbamate ; 2-methyl-2-sec-butyl-1,3-propanedioldicarbamate ; 2-sec-Butyl-2-methyl-1,3-propanediol dicarbamate ; 2-sec-butyl-2-methyl-1,3-propanedioldicarbamate ; 2-sec-Butyl-2-methyltrimethylene dicarbamate
Mebutamate Toxicity Data With Reference
| 1. | orl-rat LD50:1160 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 134 (1961),356. | ||
| 2. | ipr-rat LD50:410 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 134 (1961),356. | ||
| 3. | orl-mus LD50:550 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 134 (1961),356. | ||
| 4. | ipr-mus LD50:460 mg/kg | JMCMAR Journal of Medicinal Chemistry. 12 (1969),462. | ||
| 5. | orl-bwd LD50:100 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 21 (1972),315. |
Mebutamate Safety Profile
Poison by ingestion. Moderately toxic by intraperitoneal route. An FDA proprietary drug. When heated to decomposition it emits toxic fumes of NOx.
Risk Statements :36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements :26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
Mebutamate Specification
Mebutamate (CAS NO.64-55-1) is a sedative and anxiolytic drug with anti-hypertensive (blood pressure lowering) effects. It has effects comparable to those of barbiturates such as secobarbital, but is only around 1/3rd the potency of secobarbital as a sedative. Side effects include dizziness and headaches.
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