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Systematic Name: (2alpha,3alpha,5alpha,17beta)-17-[(1-methoxycyclopentyl)oxy]-2,3-epithioandrostane
Synonyms of Mepitiostane (CAS NO.21362-69-6): 2-alpha,3-alpha-Epithio-17-beta-yl 1-methoxycyclopentyl ether ; Androstane, 2,3-epithio-17-((1-methoxycyclopentyl)oxy)-, (2-alpha,3-alpha,5-alpha,17-beta) ; Cyclopentanone, 2-alpha, 3-alpha-epithio-5-alpha-androstan-17-beta-yl methyl acetal ; Mepitiostano ; Mepitiostanum ; 5-alpha-Androstane, 2-alpha,3-alpha-epithio-17-beta-(1-methoxycyclopentyloxy)-
CAS NO: 21362-69-6
Molecular Formula: C25H40O2S
Molecular Weight : 404.6489
Molecular Structure:
H bond acceptors: 2
H bond donors: 0
Freely Rotating Bonds: 3
Polar Surface Area: 43.76 Å2
Index of Refraction: 1.568
Molar Refractivity: 116.921 cm3
Molar Volume: 357.305 cm3
Surface Tension: 44.397 dyne/cm
Density: 1.133 g/cm3
Flash Point: 247.247 °C
Enthalpy of Vaporization: 72.209 kJ/mol
Boiling Point: 485.211 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Mepitiostane (CAS NO.21362-69-6) is an anabolic steroid,which is purported to also have anti-estrogen properties.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
human | TDLo | oral | 400ug/kg (0.4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Cancer Vol. 41, Pg. 758, 1978. |
mouse | LD | intraperitoneal | > 6130mg/kg (6130mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978. | |
mouse | LD | oral | > 6130mg/kg (6130mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978. | |
mouse | LD | subcutaneous | > 6130mg/kg (6130mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978. | |
rat | LD | intraperitoneal | > 5gm/kg (5000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978. | |
rat | LD | oral | > 5gm/kg (5000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978. | |
rat | LD | subcutaneous | > 5gm/kg (5000mg/kg) | Oyo Yakuri. Pharmacometrics. Vol. 16, Pg. 779, 1978. |
Human systemic effects by ingestion: dermatitis, liver changes, and transaminase activity. Experimental reproductive effects. When Mepitiostane (CAS NO.21362-69-6) is heated to decomposition, it emits toxic fumes of SOx.