Basic Information | Post buying leads | Suppliers |
IUPAC Name: Sodium; [3-[carboxylato-(2-methoxybenzoyl)amino]-2-methoxypropyl]mercury; 1,3-dimethyl-7H-purine-2,6-dione; hydrate
Synonyms of Mersalyl theophylline (CAS NO.63869-00-1): Salyrgan theophylline ; Sodium o-((3-hydroxymercuri-2-methoxypropyl)carbamyl)phenoxyacetate and theophylline ; Mercury, (3-(alpha-carboxy-o-anisamido)-2-methoxypropyl)hydroxy-, sodium salt, compd. with theophylline (1:1)
CAS NO: 63869-00-1
Molecular Formula: C20H25HgN5NaO8
Molecular Weight : 687.021
Molecular Structure:
H bond acceptors: 6
H bond donors: 1
Freely Rotating Bonds: 7
Polar Surface Area: 76.07Å2
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | subcutaneous | 253mg/kg (253mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 336, 1952. | |
mouse | LDLo | intraperitoneal | 131mg/kg (131mg/kg) | Compilation of LD50 Values of New Drugs. | |
mouse | LDLo | oral | 530mg/kg (530mg/kg) | Compilation of LD50 Values of New Drugs. | |
rat | LD50 | intramuscular | 37mg/kg (37mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 336, 1952. |
Mercury and its compounds are on the Community Right-To-Know List.
Poison by intramuscular route. Moderately toxic by ingestion. When Mersalyl theophylline (CAS NO.63869-00-1) is heated to decomposition ,it emits very toxic fumes of Hg, Na2O, and NOx. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC and THEOPHYLLINE.
OSHA PEL: CL 0.1 mg(Hg)/m3 (skin)
ACGIH TLV: TWA 0.1 mg(Hg)/m3 (skin); BEI: 35 µg/g creatinine total inorganic mercury in urine preshift; 15 µg/g creatinine total inorganic mercury in blood at end of shift at end of workweek.
DFG MAK: Confirmed Animal Carcinogen with Unknown Relevance to Humans
NIOSH REL: (Mercury, Aryl and Inorganic) CL 0.1 mg/m3 (skin)