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Cas Database |
| Name |
Methedrine |
EINECS | N/A |
| CAS No. | 51-57-0 | Density | g/cm3 |
| PSA | 12.03000 | LogP | 3.02990 |
| Solubility | N/A | Melting Point |
166-168oC |
| Formula | C10H15 N . Cl H | Boiling Point | 215.5°Cat760mmHg |
| Molecular Weight | 185.697 | Flash Point | 86.8°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of NOx and HCl. See also BENZEDRINE and various amphetamines. | Risk Codes | R25 |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Benzeneethanamine,N,a-dimethyl-, hydrochloride, (S)-;Benzeneethanamine, N,a-dimethyl-, hydrochloride, (aS)- (9CI); Phenethylamine, N,a-dimethyl-, hydrochloride, (S)-(+)- (8CI);(+)-2-Methylamino-2-phenylpropane hydrochloride; (+)-L-Methamphetaminehydrochloride; (+)-Methamphetamine chloride; (+)-Methamphetamine hydrochloride;(+)-Methylamphetamine hydrochloride; (+)-N,a-Dimethylphenethylamine hydrochloride;(+)-N-Methylamphetamine hydrochloride; Adipex; Amphedroxyn; D-Methamphetaminehydrochloride; Deofed; Desfedrin; Desoxo 5; Desoxyfed; Desoxyn; Desoxyne;Destim; Desyphed; Dexoval; Dextim; Doxephrin; Doxyfed; Drinalfa; Efroxine;Eufodrinal; Gerobit; Gerovit; Hiropon; Isophen; Madrine; Metamphetaminehydrochloride; Meth; Methampex; Methamphetamine hydrochloride;Methamphetaminium chloride; Methedrine; Methedrine hydrochloride;Methylamphetamine hydrochloride; Methylisomin; Methylisomyn;N-Methylamphetamine hydrochloride; NSC 169505; Norodin hydrochloride; Pervitin;Philopon; S-(+)-Methamphetamine hydrochloride; Semoxydrine; Soxysympamine;Speed; Syndrox; Tonedron; d-Deoxyephedrine hydrochloride; d-Desoxyephedrinehydrochloride; d-Methamphetamine hydrochloride; d-Methamphetaminehydrochloride; d-Methylamphetamine hydrochloride |
Article Data | 5 |
Methedrine Chemical Properties
IUPAC Name: (2S)-N-Methyl-1-phenylpropan-2-amine hydrochloride
Synonyms: (+)-N,A-Dimethylphenethylamine Hydrochloride ; (+)-N-Methylamphetamine hydrochloride ; (2S)-N-Méthyl-1-phénylpropan-2-amine chlorhydrate ; (2S)-N-Methyl-1-phenylpropan-2-amine hydrochloride (1:1) ; (2S)-N-Methyl-1-phenylpropan-2-aminhydrochlorid ; (aS)-N,a-Dimethylbenzeneethanamine Hydrochloride ; (S)-(+)-N,a-Dimethylphenethylamine Hydrochloride
CAS NO: 51-57-0
Molecular Formula of Methedrine (CAS NO.51-57-0) :C10H16ClN
Molecular Weight of Methedrine (CAS NO.51-57-0) : 185.69
Molecular Structure of Methedrine (CAS NO.51-57-0) : 
EINECS: 200-106-9
Mol File: 51-57-0.mol
Flash Point: 86.8 °C
Enthalpy of Vaporization: 45.19 kJ/mol
Boiling Point: 215.5 °C at 760 mmHg
Vapour Pressure: 0.147 mmHg at 25°C
Methedrine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 90mg/kg (90mg/kg) | Schweizerische Medizinische Wochenschrift. Vol. 84, Pg. 351, 1954. | |
| mammal (species unspecified) | LD50 | intravenous | 9500ug/kg (9.5mg/kg) | German Offenlegungsschrift Patent Document. Vol. #2901868, | |
| mammal (species unspecified) | LD50 | subcutaneous | 14mg/kg (14mg/kg) | German Offenlegungsschrift Patent Document. Vol. #2901868, | |
| man | TCLo | inhalation | 28mg/kg (28mg/kg) | BEHAVIORAL: EXCITEMENT CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION | Veterinary and Human Toxicology. Vol. 41, Pg. 28, 1999. |
| mouse | LD50 | intraperitoneal | 15mg/kg (15mg/kg) | "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 346, 1972. | |
| mouse | LD50 | intravenous | 6300ug/kg (6.3mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02170, | |
| mouse | LD50 | subcutaneous | 7560ug/kg (7.56mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Journal of Pharmacology and Experimental Therapeutics. Vol. 87, Pg. 214, 1946. |
| rat | LD50 | subcutaneous | 10930ug/kg (10.93mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 253, Pg. 466, 1990. |
Methedrine Consensus Reports
EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.
Methedrine Safety Profile
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of NOx and HCl. See also BENZEDRINE and various amphetamines.
Hazard Codes 
T
Risk Statements 25
R25 :Toxic if swallowed.
Safety Statements 45
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR 3249
RTECS SH5455000
HazardClass 6.1(b)
PackingGroup III
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