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Morphinium Chloride

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Name

Morphinium Chloride

EINECS N/A
CAS No. 52-26-6 Density g/cm3
PSA 188.84000 LogP 2.70000
Solubility N/A Melting Point about 200° (dec)
Formula C17H19 N O3 . Cl H Boiling Point 476.2°Cat760mmHg
Molecular Weight 321.804 Flash Point 241.8°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intraperitoneal, intravenous, parenteral, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also (−)-MORPHINE. Risk Codes 11-23/24/25-39/23/24/25
Molecular Structure Molecular Structure of 52-26-6 (MORPHINIUM CHLORIDE) Hazard Symbols F,T
Synonyms

Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-methyl- (5a,6a)-, hydrochloride (9CI); Morphinan-3,6a-diol, 7,8-didehydro-4,5a-epoxy-17-methyl-, hydrochloride (8CI); (-)-Morphinehydrochloride; Ampek; Epimore; Morphine chlorhydrate; Morphine hydrochloride;Morphine monohydrochloride; Opso; Pacif; Pacif capsules; Theba-Intran;Thebametten

Article Data 1

Morphinium Chloride Chemical Properties

Chemistry informtion about  Morphinium Chloride (52-26-6) is:
Synonyms: 6-Alpha-Diol,7,8-Didehydro-4,5-Alpha-Epoxy-17-Methyl-Morphinan-Hydrochlo;Ampek ; Morphinan-3,6-Diol,7,8-Didehydro-4,5-Epoxy-17-Methyl-,Hydrochloride,(5-Alpha ; Morphinechlorhydrate ; Morphinechloride ; Theba-Intran;Morphin-Hcl ; Morphinium Chloride
MF: C17H20ClNO3
MW: 321.8
EINECS: 200-136-2 
Flash Point: 241.8 °C
Boiling Point: 476.2 °C at 760 mmHg
Vapour Pressure: 7.06E-10 mmHg at 25°C 
Enthalpy of Vaporization: 77.95 kJ/mol
Storage temp.: −20°C
Following is the molecular structure of  Morphinium Chloride (52-26-6) is:

Morphinium Chloride Uses

 Morphinium Chloride (52-26-6) can be used as an analgesic to relieve and as an antitussive for severe cough.

Morphinium Chloride Toxicity Data With Reference

1.    

orl-rat LD50:335 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 115 (1958),213.
2.    

scu-rat LD50:480 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 115 (1958),213.
3.    

ivn-rat LD50:265 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 115 (1958),213.
4.    

orl-mus LD50:745 mg/kg

    JJPAAZ    Japanese Journal of Pharmacology. 18 (1968),406.
5.    

ipr-mus LD50:148 mg/kg

    BJPCBM    British Journal of Pharmacology. 73 (1981),887.
6.    

scu-mus LD50:354 mg/kg

    KSRNAM    Kiso to Rinsho. Clinical Report. 5 (1971),1787.
7.    

ivn-mus LD50:180 mg/kg

    ATSUDG    Archives of Toxicology, Supplement. 7 (1984),90.
8.    

par-mus LD50:440 mg/kg

    WKMRAH    Wakayama Medical Report. 24 (4)(1983),65.
9.    

ivn-dog LD50:175 mg/kg

    CPBTAL    Chemical and Pharmaceutical Bulletin. 7 (1959),372.

Morphinium Chloride Consensus Reports

EPA Genetic Toxicology Program.

Morphinium Chloride Safety Profile

Poison by ingestion, intraperitoneal, intravenous, parenteral, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also (−)-MORPHINE.
Hazard Codes: 
F: Flammable
T: Toxic
Risk Statements:
R11: Highly flammable. 
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
R39/23/24/25: Danger of very serious irreversible effects and toxic by inhalation, in contact with skin and if swallowed.
Safety Statements:
S7: Keep container tightly closed. 
S16: Keep away from sources of ignition.
S24: Avoid contact with skin.
S33: Take precautionary measures against static discharges.
S36/37: Wear suitable protective clothing and gloves.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 1230 3/PG 2
WGK Germany: 1

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