The N-Methyl-N-(trimethylsilyl)acetamide with the CAS number 7449-74-3 is also called Acetamide,N-methyl-N-(trimethylsilyl)-. Its molecular formula is C₆H₁₅NOSi. The EINECS registry number is 231-217-0. This chemical belongs to the following product categories: (1)Analytical Chemistry; (2)GC Derivatizing Reagents; (3)Si (Classes of Silicon Compounds); (4)Silylacetamides; (5)Silylation (GC Derivatizing Reagents); (6)Si-N Compounds; (7)Trimethylsilylation (GC Derivatizing Reagents).

The properties of the N-Methyl-N-(trimethylsilyl)acetamide are: (1)ACD/LogP: 0.57; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.57; (4)ACD/LogD (pH 7.4): 0.57; (5)ACD/BCF (pH 5.5): 1.59; (6)ACD/BCF (pH 7.4): 1.59; (7)ACD/KOC (pH 5.5): 48.47; (8)ACD/KOC (pH 7.4): 48.47; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 20.31 Å²; (13)Index of Refraction: 1.418; (14)Molar Refractivity: 42.31 cm³; (15)Molar Volume: 167.6 cm³; (16)Polarizability: 16.77×10^-24cm³; (17)Surface Tension: 21.4 dyne/cm; (18)Enthalpy of Vaporization: 37.67 kJ/mol; (19)Vapour Pressure: 6.41 mmHg at 25°C.

Preparation: This chemical can be prepared by the reaction of N-methyl-acetamide and chloro-trimethyl-silane. This reaction needs reagent triethylamine.

Uses: This chemical can react with 4-(2-amino-ethyl)-benzene-1,2-diol; hydrochloride to prepare 3,4-Dihydroxyphenaethylamin(TMS)₄. This reaction's temperature is 80 °C. The reaction time is 4.0 hours. The yield is 84%.

While using this chemical, you should be very cautious. This chemical is flammable. It is not only irritating to skin, but also irritating to eyes and respiratory system. Therefore, you should take the following instructions. Firstly, you should wear suitable protective clothing, gloves and eye/face protection. Then you should keep this chemical away from sources of ignition.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(N(C)[Si](C)(C)C)C
(2)InChI: InChI=1/C6H15NOSi/c1-6(8)7(2)9(3,4)5/h1-5H3
(3)InChIKey: QHUOBLDKFGCVCG-UHFFFAOYAD