IUPAC Name: 3-[[2-[[6-amino-2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[1-[[1-[[1-[[2-[[1-[(1-
amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Synonyms: ALPHA-NEUROKININ ; HKTDSFVGLM-NH₂ ; HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH₂ ; H-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH₂ ; SUBSTANCE K (HUMAN, PORCINE, RAT, MOUSE) ; SUBSTANCE K;NKA ; NEUROKININ A
CAS NO: 86933-74-6
Molecular Formula of Neurokinin A (CAS NO. 86933-74-6) : C₅₀H₈₀N₁₄O₁₄S
Molecular Weight of Neurokinin A (CAS NO. 86933-74-6) : 1133.32
Molecular Struture of Neurokinin A (CAS NO. 86933-74-6) :
Mol File: 86933-74-6.mol
Index of Refraction: 1.58
Surface Tension: 60.9 dyne/cm
Density: 1.305 g/cm³
Flash Point: 927.9 °C
Enthalpy of Vaporization: 264.19 kJ/mol
Boiling Point: 1610.7 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Storage temp: -20°C
Product Categories: Tachykinin receptor

Neurokinin A (CAS NO. 86933-74-6) is mediating contraction of the rat colon and bronchoconstriction through the non-adrenergic non-cholinergic nervous system (a branch of the vagal system).

WGK Germany 3
F 10-21

Neurokinin A (CAS NO. 86933-74-6) (formerly known as substance K) is a member of the tachykinin family of neuropeptide neurotransmitters. It is produced from the same preprotachykinin A gene as the neuropeptide substance P. It has various roles in the body of humans and other animals. One specific example is mediating contraction of the rat colon and bronchoconstriction through the non-adrenergic non-cholinergic nervous system (a branch of the vagal system). Neuropeptide K (which has also been called neurokinin K)and neuropeptide gamma are N-terminally longer versions of neurokinin A, produced from the same splice forms of the same gene, which appear to be final peptide products in some tissues.