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| CAS No.: | 86933-74-6 |
|---|---|
| Name: | NEUROKININ A |
| Molecular Structure: | |
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| Formula: | C50H80 N14 O14 S |
| Molecular Weight: | 1133.34 |
| Synonyms: | Kassinin,1-de-L-aspartic acid-2-de-L-valine-3-L-histidine-5-L-threonine-7-L-serine-;L-Methioninamide, L-histidyl-L-lysyl-L-threonyl-L-a-aspartyl-L-seryl-L-phenylalanyl-L-valylglycyl-L-leucyl-;Neurokinin A (Python molurus);Neurokinin A (alligator);Neurokinin A (pigspinal cord);Neurokinin a;Neurokinin a (pig spinal cord);Neurokinin a (porcine);Neuromedin L;Neuromedin L (pig spinalcord);Porcine neurokinin A;Substance K; |
| Density: | 1.305 g/cm3 |
| Boiling Point: | 1610.7 °C at 760 mmHg |
| Flash Point: | 927.9 °C |
| Solubility: | Soluble in 5% acetic acid |
| Appearance: | White to off-white lyophilized solid |
| Risk Codes: | R20/21/22: |
| Safety: | S36 |
| PSA: | 488.77000 |
| LogP: | 1.05310 |
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Chemistry
IUPAC Name: 3-[[2-[[6-amino-2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[1-[[1-[[1-[[2-[[1-[(1-
amino-4-methylsulfanyl-1-oxobutan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Synonyms: ALPHA-NEUROKININ ; HKTDSFVGLM-NH2 ; HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 ; H-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2 ; SUBSTANCE K (HUMAN, PORCINE, RAT, MOUSE) ; SUBSTANCE K;NKA ; NEUROKININ A
CAS NO: 86933-74-6
Molecular Formula of Neurokinin A (CAS NO. 86933-74-6) : C50H80N14O14S
Molecular Weight of Neurokinin A (CAS NO. 86933-74-6) : 1133.32
Molecular Struture of Neurokinin A (CAS NO. 86933-74-6) : 
Mol File: 86933-74-6.mol
Index of Refraction: 1.58
Surface Tension: 60.9 dyne/cm
Density: 1.305 g/cm3
Flash Point: 927.9 °C
Enthalpy of Vaporization: 264.19 kJ/mol
Boiling Point: 1610.7 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Storage temp: -20°C
Product Categories: Tachykinin receptor
Uses
Neurokinin A (CAS NO. 86933-74-6) is mediating contraction of the rat colon and bronchoconstriction through the non-adrenergic non-cholinergic nervous system (a branch of the vagal system).
Safety Profile
WGK Germany 3
F 10-21
Specification
Neurokinin A (CAS NO. 86933-74-6) (formerly known as substance K) is a member of the tachykinin family of neuropeptide neurotransmitters. It is produced from the same preprotachykinin A gene as the neuropeptide substance P. It has various roles in the body of humans and other animals. One specific example is mediating contraction of the rat colon and bronchoconstriction through the non-adrenergic non-cholinergic nervous system (a branch of the vagal system). Neuropeptide K (which has also been called neurokinin K)and neuropeptide gamma are N-terminally longer versions of neurokinin A, produced from the same splice forms of the same gene, which appear to be final peptide products in some tissues.