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Naftalofos

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Name

Naftalofos

EINECS 216-078-6
CAS No. 1491-41-4 Density 1.41 g/cm3
PSA 93.64000 LogP 2.56240
Solubility N/A Melting Point 174-179°
Formula C16H16NO6P Boiling Point 487.3 °C at 760 mmHg
Molecular Weight 349.28 Flash Point 248.5 °C
Transport Information UN 2783 Appearance white powder
Safety 36/37-45 Risk Codes 24/25
Molecular Structure Molecular Structure of 1491-41-4 (Naftalofos) Hazard Symbols ToxicT
Synonyms

Naphthalimide,N-hydroxy-, diethyl phosphate (6CI,7CI,8CI);2-[(Diethoxyphosphinyl)oxy]-1H-benz[de]isoquinoline-1,3(2H)-dione;2-[(Diethoxyphosphoryl)oxy]-1H-benzo[de]isochinolin-1,3(2H)-dion;Maretin;N-Hydroxynaphthalimide diethyl phosphate;Naphthalophos;O,O-Diethyl N-hydroxynaphthalimide phosphate;Rametin;

 

Naftalofos Specification

The CAS registry number of is 1491-41-4. Its EINECS registry number is 216-078-6. The IUPAC name is (1,3-dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate. In addition, the molecular formula is C16H16NO6P and the molecular weight is 349.28. It is also called 1H-Benz[de]isoquinoline-1,3(2H)-dione,2-[(diethoxyphosphinyl)oxy]-. What's more, it should be stored in a cool and dry place.

Physical properties about this chemical are: (1)ACD/LogP: 2.01 ; (2)ACD/LogD (pH 5.5): 2.01; (3)ACD/LogD (pH 7.4): 2.01; (4)ACD/BCF (pH 5.5): 19.8; (5)ACD/BCF (pH 7.4): 19.8; (6)ACD/KOC (pH 5.5): 294.92; (7)ACD/KOC (pH 7.4): 294.92; (8)#H bond acceptors: 7; (9)#Freely Rotating Bonds: 6; (10)Polar Surface Area: 91.95 Å2; (11)Index of Refraction: 1.612; (12)Molar Refractivity: 86.11 cm3; (13)Molar Volume: 247.6 cm3; (14)Polarizability: 34.14 ×10-24cm3; (15)Surface Tension: 59 dyne/cm; (16)Density: 1.41 g/cm3; (17)Flash Point: 248.5 °C; (18)Enthalpy of Vaporization: 75.32 kJ/mol; (19)Boiling Point: 487.3 °C at 760 mmHg; (20)Vapour Pressure: 1.2E-09 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is toxic in contact with skin and if swallowed. During using it, wear suitable protective clothing and gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.).

You can still convert the following datas into molecular structure:
(1)SMILES: O=P(OCC)(OCC)ON3C(=O)c2cccc1cccc(c12)C3=O
(2)InChI: InChI=1/C16H16NO6P/c1-3-21-24(20,22-4-2)23-17-15(18)12-9-5-7-11-8-6-10-13(14(11)12)16(17)19/h5-10H,3-4H2,1-2H3
(3)InChIKey: QNSIFYWAPWSAIJ-UHFFFAOYAX

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
chicken LD50 oral 43300ug/kg (43.3mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 11, Pg. 49, 1967.
domestic animals - goat/sheep LDLo oral 200mg/kg (200mg/kg)   Fortschritte der Arzneimittelforschung. Progress in Drug Research. Vol. 17, Pg. 108, 1973.
mouse LD50 oral 50mg/kg (50mg/kg)   Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 3, 1966.
rat LD50 oral 70mg/kg (70mg/kg)   World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat LD50 skin 140mg/kg (140mg/kg)   Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 45, 1978.

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