EPA Genetic Toxicology Program.

The Norethandrolone, with the CAS registry number 52-78-8, is also known as 17a-Ethyl-19-nortestosterone. It belongs to the product categories of Intermediates & Fine Chemicals; Pharmaceuticals; Steroids; Steroid and Hormone. Its EINECS number is 200-153-5. This chemical's molecular formula is C₂₀H₃₀O₂ and molecular weight is 302.45. What's more, its systematic name is (17β)-17-ethyl-17-hydroxyester-4-en-3-one. Its classification codes are: (1)Anabolic Agents; (2)Hormone; (3)Hormones; (4)Hormones, Hormone Substitutes, and Hormone Antagonists; (5)Human Data; (6)Mutation data; (7)Reproductive Effect. Norethandrolone is an anabolic steroid.

Physical properties of Norethandrolone are: (1)ACD/LogP: 3.788; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.79; (4)ACD/LogD (pH 7.4): 3.79; (5)ACD/BCF (pH 5.5): 445.21; (6)ACD/BCF (pH 7.4): 445.21; (7)ACD/KOC (pH 5.5): 2738.08; (8)ACD/KOC (pH 7.4): 2738.08; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 37.3 Å²; (13)Index of Refraction: 1.555; (14)Molar Refractivity: 87.744 cm³; (15)Molar Volume: 273.19 cm³; (16)Polarizability: 34.785×10^-24cm³; (17)Surface Tension: 44.03 dyne/cm; (18)Density: 1.107 g/cm³; (19)Flash Point: 190.529 °C; (20)Enthalpy of Vaporization: 81.398 kJ/mol; (21)Boiling Point: 447.136 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

Uses of Norethandrolone: it can be used to produce 17-hydroxy-19-nor-5a,17bH-pregnan-3-one and 17-hydroxy-19-nor-5b,17bH-pregnan-3-one at the temperature of 20 °C. It will need reagents potassium hydroxide, hydrogen and solvents methanol, H₂O with the reaction time of 2 hours. This reaction will also need catalyst Pd/C. The yield is about 81%.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C4\C=C3/[C@@H]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)CC)[C@@H]2CC3)C)CC4
(2)Std. InChI: InChI=1S/C20H30O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h12,15-18,22H,3-11H2,1-2H3/t15-,16+,17+,18-,19-,20-/m0/s1
(3)Std. InChIKey: ZDHCJEIGTNNEMY-XGXHKTLJSA-N