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Olivomycin

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Name

Olivomycin

EINECS N/A
CAS No. 11006-70-5 Density 1.48g/cm3
PSA N/A LogP N/A
Solubility N/A Melting Point N/A
Formula N/A Boiling Point 1075.3°C at 760 mmHg
Molecular Weight 940.9771 Flash Point 312.5°C
Transport Information N/A Appearance N/A
Safety Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human mutation data reported. See also OLIVOMYCIN A; OLIVOMYCIN D. Risk Codes N/A
Molecular Structure Molecular Structure of 11006-70-5 (Olivomycin) Hazard Symbols N/A
Synonyms

NSC 76411;Olivomycine

 

Olivomycin Chemical Properties

IUPAC Name: (2S,3S)-3-[(1S,3S,4R)-3,4-Dihydroxy-1-methoxy-2-oxopentyl]-2-[(2R,4S,5S,6S)-4-[(4S,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-5-hydroxy-6-methyloxan-2-yl]oxy-8,9-dihydroxy-6-[(2S,4R,5S,6R)-5-hydroxy-4-[(2S,4S,5S,6S)-4-hydroxy-5-methoxy-6-methyloxan-2-yl]oxy-6-methyloxan-2-yl]oxy-3,4-dihydro-2H-anthracen-1-one
Synonyms of Olivomycin (CAS NO.11006-70-5) : Oligomycin A, mixt. with oligomycin B ; Oligomycin B, mixt. with oligomycin A ; Olivomycin ; Toyomycin R
InChI:InChI=1/C45H64O21/c1-16(46)36(50)42(56)44(58-7)24-10-22-8-21-9-23(63-32-14-28(38(52)18(3)60-32)65-31-13-27(49)43(57-6)20(5)62-31)11-25(47)34(21)40(54)35(22)41(55)45(24)66-33-15-29(39(53)19(4)61-33)64-30-12-26(48)37(51)17(2)59-30/h8-9,11,16-20,24,26-33,36-39,43-54H,10,12-15H2,1-7H3/t16-,17+,18-,19+,20+,24+,26+,27+,28-,29+,30?,31+,32+,33-,36+,37+,38+,39+,43-,44+,45+/m1/s1
CAS NO:11006-70-5
Molecular Formula:C45H64O21
Molecular Weight :940.9771
Molecular Structure :
Index of Refraction: 1.635
Surface Tension: 77.4 dyne/cm
Density: 1.48 g/cm3
Flash Point: 312.5 °C
Enthalpy of Vaporization: 165.16 kJ/mol
Boiling Point: 1075.3 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C

Olivomycin Uses

 Olivomycin (CAS NO.11006-70-5) is used as  intermediate in organic synthesis.

Olivomycin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 5100ug/kg (5.1mg/kg)   Antibiotiki. Vol. 21, Pg. 258, 1976.
mouse LD50 intravenous 5mg/kg (5mg/kg)   "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1322, 1978.
mouse LD50 subcutaneous 8400ug/kg (8.4mg/kg)   Antibiotiki. Vol. 21, Pg. 258, 1976.
rabbit LD50 intravenous 1850ug/kg (1.85mg/kg)   Antibiotiki. Vol. 21, Pg. 258, 1976.
rat LD50 intraperitoneal 6600ug/kg (6.6mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL" Antibiotiki. Vol. 24, Pg. 120, 1979.
rat LD50 intravenous 1900ug/kg (1.9mg/kg)   Antibiotiki. Vol. 21, Pg. 258, 1976.
rat LD50 subcutaneous 1700ug/kg (1.7mg/kg)   Antibiotiki. Vol. 21, Pg. 258, 1976.

Olivomycin Safety Profile

 Olivomycin (CAS NO.11006-70-5) is poisonous by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human mutation data reported. See also OLIVOMYCIN A; OLIVOMYCIN D.

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