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| Name |
Oxanamide |
EINECS | N/A |
| CAS No. | 126-93-2 | Density | 1.028g/cm3 |
| PSA | 56.61000 | LogP | 1.96910 |
| Solubility | N/A | Melting Point |
90-91° |
| Formula | C8H15 N O2 | Boiling Point | 292.2°Cat760mmHg |
| Molecular Weight | 157.213 | Flash Point | 145.8°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Hexanamide,2,3-epoxy-2-ethyl- (6CI,7CI,8CI); Oxiranecarboxamide, 2-ethyl-3-propyl- (9CI);2,3-Epoxy-2-ethylhexanamide; 2-Ethyl-3-propyl-2,3-epoxypropionamide;2-Ethyl-3-propylglycidamide; Oxanamid; Oxanamide; Quiactin |
Oxanamide Chemical Properties
IUPAC Name: 2-Ethyl-3-propyloxirane-2-carboxamide
Synonyms of Oxanamide (CAS NO.126-93-2) : Oxanamide ; 2-Ethyl-3-propyl-2-oxiranecarboxamide ; 2-Ethyl-3-propyloxiranecarboxamide ; 2-Oxiranecarboxamide, 2-ethyl-3-propyl-
CAS NO:126-93-2
Molecular Formula:C8H15NO2
Molecular Weight:157.2102
Molecular Structure:.png)
Index of Refraction: 1.463
Surface Tension: 34.5 dyne/cm
Density: 1.028 g/cm3
Flash Point: 145.8 °C
Enthalpy of Vaporization: 53.17 kJ/mol
Boiling Point: 292.2 °C at 760 mmHg
Vapour Pressure: 0.00186 mmHg at 25°C
Oxanamide Uses
Oxanamide (CAS NO.126-93-2) is an anxiolytic and muscle relaxant medication which can produce sedative and hypnotic effects in sufficiently high doses. It was efficacious in the treatment of anxiety resulting from premenstrual syndrome, menopause, and various other causes, with minimal sedation or other side effects.
Oxanamide Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 605mg/kg (605mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 134, Pg. 60, 1961. | |
| mouse | LD50 | oral | 1220mg/kg (1220mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 103, Pg. 101, 1960. |
| rabbit | LD50 | intravenous | > 360mg/kg (360mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 96, Pg. 209, 1949. | |
| rat | LD50 | oral | 1250mg/kg (1250mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 7, Pg. 262, 1948. |
Oxanamide Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
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