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| Name |
Palytoxin |
EINECS | N/A |
| CAS No. | 11077-03-5 | Density | 1.374±0.06 g/cm3(Predicted) |
| PSA | 994.95000 | LogP | -6.11190 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C129H221 N3 O53 | Boiling Point | N/A |
| Molecular Weight | 2662.16 | Flash Point | N/A |
| Transport Information | N/A | Appearance | N/A |
| Safety | A deadly poison by intraperitoneal, parenteral, subcutaneous, intravenous, intramuscular, and intratracheal routes. A skin and severe eye irritant. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | 26/27/28 |
| Molecular Structure |
|
Hazard Symbols |
|
| Synonyms |
Palytoxin(8CI); 2,6-Dioxabicyclo[3.2.1]octane, palytoxin deriv.;2,7-Dioxabicyclo[2.2.1]heptane, palytoxin deriv.;6,8-Dioxabicyclo[3.2.1]octane, palytoxin deriv. |
Palytoxin Chemical Properties
Product Name: Palytoxin
Synonyms of Palytoxin (CAS NO.11077-03-5) : Palytoxin (8CI) ; 2,6-Dioxabicyclo[3.2.1]octane, palytoxin deriv. ; 2,7-Dioxabicyclo[2.2.1]heptane, palytoxin deriv. ; 6,8-Dioxabicyclo[3.2.1]octane, palytoxin deriv.
CAS NO:11077-03-5
Molecular Formula:C129H221N3O53
Molecular Weight :2662.1233
Molecular Structure :.png)
Index of Refraction: 1.606
Surface Tension: 71.618 dyne/cm
Density: 1.374 g/cm3
Palytoxin Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | 33ng/kg (0.000033mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| dog | LDLo | parenteral | 50ng/kg (0.00005mg/kg) | CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE CARDIAC: OTHER CHANGES VASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTION | "Food-Drugs from the Sea, Proceedings of the Conference, 4th, Mayaguez, PR, 1974," Webber, H.H., and G.D. Ruggieri, eds., Washington, DC, Marine Technology Soc., 1976Vol. -, Pg. 311, 1976. |
| guinea pig | LD50 | intravenous | 110ng/kg (0.00011mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| guinea pig | LDLo | parenteral | 25ng/kg (0.000025mg/kg) | CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE VASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTION CARDIAC: OTHER CHANGES | "Food-Drugs from the Sea, Proceedings of the Conference, 4th, Mayaguez, PR, 1974," Webber, H.H., and G.D. Ruggieri, eds., Washington, DC, Marine Technology Soc., 1976Vol. -, Pg. 311, 1976. |
| monkey | LD50 | intravenous | 78ng/kg (0.000078mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| mouse | LD50 | intraperitoneal | 50ng/kg (0.00005mg/kg) | Annual Review of Pharmacology and Toxicology. Vol. 26, Pg. 117, 1986. | |
| mouse | LD50 | intravenous | 150ng/kg (0.00015mg/kg) | Science. Vol. 172, Pg. 495, 1971. | |
| mouse | LD50 | unreported | 600ng/kg (0.0006mg/kg) | Igaku No Ayumi. Progress in Medicine. Vol. 112, Pg. 861, 1980. | |
| rabbit | LD50 | intravenous | 25ng/kg (0.000025mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LD50 | intramuscular | 240ng/kg (0.00024mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LD50 | intraperitoneal | 710ng/kg (0.00071mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LD50 | intratracheal | 360ng/kg (0.00036mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LD50 | intravenous | 89ng/kg (0.000089mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LD50 | oral | > 40ug/kg (0.04mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LD50 | rectal | > 10ug/kg (0.01mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LD50 | subcutaneous | 400ng/kg (0.0004mg/kg) | Toxicology and Applied Pharmacology. Vol. 34, Pg. 214, 1975. | |
| rat | LDLo | parenteral | 25ng/kg (0.000025mg/kg) | CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE CARDIAC: OTHER CHANGES VASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTION | "Food-Drugs from the Sea, Proceedings of the Conference, 4th, Mayaguez, PR, 1974," Webber, H.H., and G.D. Ruggieri, eds., Washington, DC, Marine Technology Soc., 1976Vol. -, Pg. 311, 1976. |
Palytoxin Safety Profile
A deadly poison by intraperitoneal, parenteral, subcutaneous, intravenous, intramuscular, and intratracheal routes. A skin and severe eye irritant. When Palytoxin (CAS NO.11077-03-5) is heated to decomposition, it emits toxic fumes of NOx.
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