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Periplocin

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Name

Periplocin

EINECS N/A
CAS No. 13137-64-9 Density 1.429g/cm3
PSA 193.83000 LogP 1.07850
Solubility 7.937g/L(cold water) Melting Point 205°C
Formula C36H56 O13 Boiling Point 877.409oC at 760 mmHg
Molecular Weight 696.82 Flash Point 272.777oC
Transport Information N/A Appearance N/A
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 13137-64-9 (Periplocoside) Hazard Symbols N/A
Synonyms

Periplocin(6CI,7CI,8CI); Periplocoside

 

Periplocin Chemical Properties

Molecular Structure:

Molecular Formula: C35H54O13
Molecular Weight: 682.7955
IUPAC Name: 3-[(3S,5S,10R,13R,14S,17R)-3-[(2R,5R)-6-[[(3R,6S)-4,6-Dihydroxy-2-methyloxan-3-yl]oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-5,14-dihydroxy-10,13-dimethyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one
Synonyms of Periplocin (CAS NO.13137-64-9): 4-18-00-02439 (Beilstein Handbook Reference) ; BRN 0075742 ; Glucoperiplocymarin ; Periplocoside ; Periplogenin + D-cymarose + D-glucose ; Periplogenin + D-cymarose + D-glucose [German] ; Card-20(22)-enolide, 3-((2,6-dideoxy-4-O-beta-D-glucopyranosyl-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-, (3-beta,5-beta)-
CAS NO: 13137-64-9 
Index of Refraction: 1.624
Molar Refractivity: 168.818 cm3
Molar Volume: 477.909 cm3
Surface Tension: 72.463 dyne/cm
Density: 1.429 g/cm3
Flash Point: 272.777 °C
Enthalpy of Vaporization: 144.868 kJ/mol
Boiling Point of Periplocin (CAS NO.13137-64-9): 877.409 °C at 760 mmHg

Periplocin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 120ug/kg (0.12mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

GASTROINTESTINAL: NAUSEA OR VOMITING
"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 193, 1963.
cat LDLo subcutaneous 2500ug/kg (2.5mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

GASTROINTESTINAL: NAUSEA OR VOMITING
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.
cat LDLo unreported 121ug/kg (0.121mg/kg)   "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 151, 1963.
frog LDLo subcutaneous 34mg/kg (34mg/kg) CARDIAC: PULSE RATE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.
rabbit LDLo subcutaneous 10mg/kg (10mg/kg) BEHAVIORAL: TREMOR

CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.
rat LDLo subcutaneous 480mg/kg (480mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 27, Pg. 449, 1926.

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