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Phalloidine

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Name

Phalloidine

EINECS 241-484-5
CAS No. 17466-45-4 Density 1.51g/cm3
PSA 316.92000 LogP -1.83500
Solubility

Stability

    Stable. Incompatible with strong oxidizing agents.

Toxicology

    Very toxic. May be fatal if swallowed, inhaled orabsorbed through the skin.

    Toxicity data

Melting Point 280-282°
Formula C35H48 N8 O11 S Boiling Point 1370.5°Cat760mmHg
Molecular Weight 788.879 Flash Point 782.6°C
Transport Information N/A Appearance white powder
Safety Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx, and NOx. Risk Codes 26/27/28
Molecular Structure Molecular Structure of 17466-45-4 (Phalloidin) Hazard Symbols
Synonyms

Cyclo[L-alanyl-D-threonyl-L-cysteinyl-(4S)-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-(4R)-4,5-dihydroxy-L-leucyl],cyclic (3?;6)-thioether;NSC 523214;Phalloidine;

Article Data 14

Phalloidine Chemical Properties

Empirical Formula  of Phalloidine (CAS NO.17466-45-4): C35H48N8O11S
Molecular Weight: 788.8676 g/mol
Index of Refraction: 1.683
Density: 1.51 g/cm3
Flash Point: 782.6 °C
Enthalpy of Vaporization: 217.3 kJ/mol
Boiling Point: 1370.5 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25 °C
Structure of Phalloidine (CAS NO.17466-45-4):
            

Phalloidine Toxicity Data With Reference

1.    

mor-rat:lvr 1 µmol/L

    CYTZAM    Cytobiologie. 17 (1978),73.
2.    

dni-rat:lvr 100 nmol/L

    TOXIA6    Toxicon. 25 (1987),1265.
3.    

ipr-mus LD50:2 mg/kg

    NEJMAG    New England Journal of Medicine. 269 (1963),223.
4.    

ivn-mus LDLo:6600 µg/kg

    AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 190 (1938),406.
5.    

orl-mam LDLo:1000 µg/kg

    CTOXAO    Clinical Toxicology. 17 (1980),45.

Phalloidine Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition,  Phalloidine (CAS NO.17466-45-4) emits toxic fumes of SOx, and NOx.

Phalloidine Specification

 Phalloidine ,its cas register number is 17466-45-4. It also can be called Cyclic(L-alanyl-D-threonyl-L-cysteinyl-cis-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-4,5-dihydroxy-L-leucyl),cyclic (3,6)-sulfide and Phalloidine .

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