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Piperazine Adipate

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Name

Piperazine Adipate

EINECS 205-569-0
CAS No. 142-88-1 Density 1.1633 (rough estimate)
PSA 98.66000 LogP 0.55280
Solubility almost transparency Melting Point 256-257°
Formula C10H20N2O4 Boiling Point 338.5 °C at 760 mmHg
Molecular Weight 232.28 Flash Point 172.7 °C
Transport Information N/A Appearance white crystals or powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 142-88-1 (Piperazine adipate) Hazard Symbols N/A
Synonyms

Hexanedioic acid,compounds,compd. with piperazine (1:1);Adipic acid, compd. with piperazine (1:1);Nometan;Pipadox;Oxypaat;Arduvermin;Adiprazine;Camin AP (TN);Camin AP;Piperascat;Piperazine adipinate;Vermicompren;Piperazine adipate (JP14);Helmirazin;Hexanedioic acid, compd. with piperazine (1:1);Adiprazina;Vermilass;hexanedioic acid; piperazine;Entacyl;Oxurasin;Dietelmin;Piperaskat;Divermex;

 

Piperazine Adipate Consensus Reports

Reported in EPA TSCA Inventory.

Piperazine Adipate Specification

Piperazine Adipate is an odorless white crystalline powder or solid, with a slightly acid taste. Piperazine Adipate(CAS NO. 142-88-1) is an alternative treatment for ascariasis caused by roundworms and Oxyuriasis by pinworms.With the Molecular Formula of C10H20N2O4 ,it is especially useful in the treatment of partial intestinal obstruction caused by Acaris worms, which is commonly seen with children. Piperazine Adipate bloks the response of the worm muscle. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled from the body.

Physical properties about Piperazine Adipate are: (1)ACD/LogP: 0.079; (2)ACD/LogD (pH 5.5): -1.56; (3)ACD/LogD (pH 7.4): -4.54; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5): 1.00; (7)ACD/KOC (pH 7.4): 1.00; (8)#H bond acceptors: 4; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 5; (11)Flash Point: 172.7 °C ; (12)Enthalpy of Vaporization: 63.95 kJ/mol; (13)Boiling Point: 338.5 °C at 760 mmHg; (14)Vapour Pressure: 1.81E-05 mmHg at 25°C

You can still convert the following datas into molecular structure:
(1)InChI=1S/C6H10O4.C4H10N2/c7-5(8)3-1-2-4-6(9)10;1-2-6-4-3-5-1/h1-4H2,(H,7,8)(H,9,10);5-6H,1-4H2;
(2)InChIKey=BVEGEKOBSPXUJS-UHFFFAOYSA-N;
(3)SmilesN1CCNCC1.C(O)(=O)CCCCC(O)=O

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1640mg/kg (1640mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 100, 1982.
mouse LD50 oral 8gm/kg (8000mg/kg)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 100, 1982.
rat LD50 oral 7900mg/kg (7900mg/kg)   Annales Pharmaceutiques Francaises. Vol. 13, Pg. 539, 1955.
 

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