Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Plafibride

Related Products

Hot Products

Basic Information Post buying leads Suppliers
Name

Plafibride

EINECS
CAS No. 63394-05-8 Density 1.251g/cm3
Solubility Melting Point
Formula C16H22 Cl N3 O4 Boiling Point
Molecular Weight 355.86 Flash Point
Transport Information Appearance
Safety Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Used as an antithrombotic agent. When heated to decomposition it emits very toxic fumes of Cl and NOx. Risk Codes
Molecular Structure Molecular Structure of 63394-05-8 (Propanamide,2-(4-chlorophenoxy)-2-methyl-N-[[(4-morpholinylmethyl)amino]carbonyl]-) Hazard Symbols
Synonyms

ITA 104;Idonor; Perifunal; Plafibride

 

Plafibride Chemical Properties

Product Name: Plafibride (CAS NO.63394-05-8)


Molecular Formula: C16H22ClN3O4
Molecular Weight: 355.86g/mol
Mol File: 63394-05-8.mol
Einecs: 264-121-2
Density: 1.251 g/cm3
Surface Tension: 46.3 dyne/cm
XLogP3-AA: 2.4
H-Bond Donor: 2
H-Bond Acceptor: 5
Structure Descriptors of Plafibride (CAS NO.63394-05-8):
  IUPAC Name: 2-(4-chlorophenoxy)-2-methyl-N-(morpholin-4-ylmethylcarbamoyl)propanamide
  Canonical SMILES: CC(C)(C(=O)NC(=O)NCN1CCOCC1)OC2=CC=C(C=C2)Cl
  InChI: InChI=1S/C16H22ClN3O4/c1-16(2,24-13-5-3-12(17)4-6-13)14(21)19-15(22)18-11-20-7-9-23-10-8-20/h3-6H,7-11H2,1-2H3,(H2,18,19,21,22) 
  InChIKey: DDDQVDIPBFGVIG-UHFFFAOYSA-N

Plafibride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 2168mg/kg (2168mg/kg)   Archivos de Farmacologia y Toxicologia. Vol. 4, Pg. 137, 1978.
hamster LD50 intraperitoneal 880mg/kg (880mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981.
hamster LD50 oral > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981.
mouse LD50 intraperitoneal 710mg/kg (710mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981.
mouse LD50 intravenous 126mg/kg (126mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981.
mouse LD50 oral 3365mg/kg (3365mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981.
rat LD50 intraperitoneal 975mg/kg (975mg/kg)   Archivos de Farmacologia y Toxicologia. Vol. 4, Pg. 137, 1978.
rat LD50 intravenous 95mg/kg (95mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981.
rat LD50 oral > 4gm/kg (4000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981.

Plafibride Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Used as an antithrombotic agent. When heated to decomposition it emits very toxic fumes of Cl and NOx.

Plafibride Specification

 Plafibride ,its CAS NO. is 63394-05-8,the synonyms is 1-(2-(p-Chlorophenoxy)-2-methylpropionyl)-3-(morpholinomethyl)urea ; BRN 0569805 ; EINECS 264-121-2 ; ITA-104 ; Idonor ; N'-Morpholinomethylurea, N-2-(p-chlorophenoxy)isobutyryl- ; N-2(p-Chlorophenoxy)-2-methylpropionyl-N'-morpholinomethylurea ; N-2(p-Chlorophenoxy)isobutyryl-N'-morpholinomethylurea ; Perifunal ; Plafibridum ; UNII-5J7C4JZ564 ; Propanamide, 2-(4-chlorophenoxy)-2-methyl-N-(((4-morpholinylmethyl)amino)carbonyl)- .

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields