Malic Acid

Base Information Edit

Chemical Name:Malic Acid
CAS No.:617-48-1
Deprecated CAS:41308-42-3,617-48-1,623158-98-5,879715-44-3,1334703-48-8,1334703-48-8,617-48-1,879715-44-3
Molecular Formula:C4H6O5
Molecular Weight:134.089
Hs Code.:2918990090
European Community (EC) Number:230-022-8, 210-514-9, 202-601-5,210-514-9,690-607-2
NSC Number:25941
UNII:817L1N4CKP
DSSTox Substance ID:DTXSID0027640
Nikkaji Number:J3.091K
Wikipedia:Malic_acid
Wikidata:Q190143
NCI Thesaurus Code:C80654
RXCUI:29209
Metabolomics Workbench ID:123508
ChEMBL ID:CHEMBL1455497
Mol file:617-48-1.mol

Synonyms:calcium (hydroxy-1-malate) hexahydrate;malate;malic acid;malic acid, (R)-isomer;malic acid, calcium salt, (1:1), (S)-isomer;malic acid, disodium salt;malic acid, disodium salt, (R)-isomer;malic acid, disodium salt, (S)-isomer;malic acid, magnesium salt (2:1);malic acid, monopotassium salt, (+-)-isomer;malic acid, potassium salt, (R)-isomer;malic acid, sodium salt, (+-)-isomer

Suppliers and Price of Malic Acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 151 raw suppliers

Chemical Property of Malic Acid Edit

Chemical Property:

Appearance/Colour:White to nearly white crystals or crystal powder
Vapor Pressure:7.19E-05mmHg at 25°C
Melting Point:130-132oC
Boiling Point:306.4oC at 760 mmHg
Flash Point:203oC
PSA：94.83000
Density:1.641 g/cm3
LogP:-1.09340
Water Solubility.:558 g/L (20℃)
XLogP3:-1.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:134.02152329
Heavy Atom Count:9
Complexity:129

Purity/Quality:: ≥99.0% ^*data from raw suppliers

Safty Information:

Pictogram(s): R22:; R34:; R42/43:;
Hazard Codes: Xi:Irritant;
Statements: R22:; R34:; R42/43:;
Safety Statements: S26:; S37/39:;

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Other Classes -> Organic Acids
Canonical SMILES:C(C(C(=O)O)O)C(=O)O
Recent ClinicalTrials:Malic Acid in Treatment of Xerostomia
Recent EU Clinical Trials:Sympthomatic and prophylactic treatment of drug induced oral dryness in elderly patients with high drug consumption.
Recent NIPH Clinical Trials:Effect of supplements containing malic acid and magnesium oxide on sleeping - a parallel randomized trial-.

Technology Process of Malic Acid

There total 130 articles about Malic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 110-17-8,26099-09-2
(2E)-but-2-enedioic acid

: 617-48-1,78644-42-5
malic acid

Guidance literature:: With sodium; iron;

Reference yield: 84.0%

: 98-01-1
furfural

: 617-48-1,78644-42-5
malic acid

: 110-16-7,26099-09-2
maleic acid

Guidance literature:: With dihydrogen peroxide; acetic acid; 5 weight percent methyltrioxorhenium on polystyrene; In water; at 20 ℃; Product distribution / selectivity;