5-Ethyl-3-imino-6-phenylphenanthridin-8-amine;hydrobromide

Base Information Edit

Chemical Name:5-Ethyl-3-imino-6-phenylphenanthridin-8-amine;hydrobromide
CAS No.:1239-45-8
Molecular Formula:C21H20BrN3
Molecular Weight:394.314
Hs Code.:29339990
Pharos Ligand ID:UA864SDLLZ5T
Mol file:1239-45-8.mol

Synonyms:

Suppliers and Price of 5-Ethyl-3-imino-6-phenylphenanthridin-8-amine;hydrobromide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
ETBR
96Tests
$ 729.00

TRC
Ethidium Bromide
25g
$ 640.00

TCI Chemical
Ethidium Bromide (0.5mg/mL in Water) (in Dropper Bottle) [for Electrophoresis]
10mL
$ 52.00

TCI Chemical
Ethidium Bromide >95.0%(HPLC)(T)
5g
$ 475.00

TCI Chemical
Ethidium Bromide >95.0%(HPLC)(T)
1g
$ 102.00

Sigma-Aldrich
Ethidium bromide ~95% (HPLC)
25g
$ 500.00

Sigma-Aldrich
Ethidium bromide BioReagent, for molecular biology, powder
25g
$ 680.00

Sigma-Aldrich
Ethidium bromide solution for fluorescence, ~1% in H2O
50 mL
$ 91.70

Sigma-Aldrich
Ethidium bromide ~95% (HPLC)
5g
$ 116.00

Sigma-Aldrich
OmniPur Ethidium Bromide - CAS 1239-45-8 - Calbiochem
5gm
$ 148.00

Total 116 raw suppliers

Chemical Property of 5-Ethyl-3-imino-6-phenylphenanthridin-8-amine;hydrobromide Edit

Chemical Property:

Appearance/Colour:Purple/maroon crystalline powder
Melting Point:260-262 °C (dec.)(lit.)
Refractive Index:1.6700 (estimate)
Flash Point:>100°C
PSA：55.92000
Density:g/cm³
LogP:2.29820
Storage Temp.:2-8°C
Solubility.:H2O: 10 mg/mL, opaque, strongly red
Water Solubility.:40 g/L (25 ºC)
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:393.08406
Heavy Atom Count:25
Complexity:765

Purity/Quality:

98%, ^*data from raw suppliers

ETBR ^*data from reagent suppliers

Safty Information:

Pictogram(s): T, T+
Hazard Codes:T,T+
Statements: 23-68-36/37/38-26-21/22-22
Safety Statements: 36/37-45-36/37/39-28A-26-22-28-63

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCN1C2=CC(=N)C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N.Br
description Ethidium Bromide (EtBr), commonly used in research laboratories as a stain for the visualization of nucleic acids in electrophoresis gels, is a toxic chemical and a potent mutagen. When used in nucleic acid staining, ethidium bromide fluoresces a red-orange to pink color under ultraviolet light and with increased fluorescence when bound to double-stranded DNA. While it is not specifically regulated as a hazardous waste, the mutagenic properties may present health hazards and disposal concerns if it is not managed properly in the laboratory.
Uses Ethidium bromide (EtBr) is a fluorescent dye widely used in molecular biology research. Early usage was as a veterinary trypanocide. It is a mutagenic compound that intercalates double-stranded DNA and RNA. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA, 25-fold on binding double-stranded DNA (although histones block binding of EtBr to DNA). Ethidium bromide has been used in multiple fluorimetric assays for nucleic acids. It has been shown to bind to single-stranded DNA (although not as strongly) and triple-stranded DNA. Because of the binding to DNA, EtBr is a powerful inhibitor of DNA polymerase.Molecular Biology-grade Powder is suitable for use in gel electrophoresis and DNA isolation procedures.Aqueous Solution (10 mg/mL) is suitable for use in gel electrophoresis and DNA isolation procedures.Molecular Biology-grade Aqueous Solution (500 mg/mL) is suitable for use in gel electrophoresis. Ethidium bromide (EtBr) is the most commonly used nucleic acid stain for PAGE or agarose gel electrophoresis. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA and 25-fold on binding double-stranded DNA so that destaining the background is not necessary with a low stain concentration (10 μg/ml). Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids. It has been shown to bind to single-stranded DNA (although not as strongly) and triple-stranded DNA. Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. Antiprotozoal (Trypanosoma). Intercalating agent and fluorescent label for DNA. antiprotozoal, intercalcates with DNA

Technology Process of 5-Ethyl-3-imino-6-phenylphenanthridin-8-amine;hydrobromide

There total 23 articles about 5-Ethyl-3-imino-6-phenylphenanthridin-8-amine;hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 52671-22-4
3,8-Bis-ethoxycarbonylamino-5-ethyl-6-phenyl-phenanthridinium; bromide

: 1239-45-8
ethidium Bromide

Guidance literature:: With sulfuric acid; at 150 ℃; for 0.333333h;

Reference yield: 57.0%

: 93840-65-4
3,8-dinitro-5-ethyl-6-phenylphenanthridinium ethyl sulfate

: 1239-45-8
ethidium Bromide

Guidance literature:: 3,8-dinitro-5-ethyl-6-phenylphenanthridinium ethyl sulfate; With sulfuric acid; iron; In ethanol; water; for 1.5h; Reflux;

With ammonia; In ethanol; water; at 25 ℃; Further stages;
DOI:10.1134/S107042721109014X

Reference yield:

: 2243-78-9
2-nitro-benzidine

: 1239-45-8
ethidium Bromide

Guidance literature:: Multi-step reaction with 6 steps

1: 92 percent / N,N-diethylaniline / ethanol / 0.17 h / Heating

2: 93 percent / iron, hydrochlorid acid / Heating; 1) water, 1 h, 2) aqueous ethanol, 20 min

3: 77 percent / nitrobenzene / Heating

4: 66 percent / POCl₃ / 0.75 h / Heating

5: N,N-dimethyl-acetamide / 0.5 h

6: 59 percent / diluted H₂SO₄ / 0.33 h / 150 °C

With hydrogenchloride; sulfuric acid; iron; N,N-diethylaniline; trichlorophosphate; In ethanol; N,N-dimethyl acetamide; nitrobenzene;