4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic acid

Base Information Edit

Chemical Name:4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic acid
CAS No.:71675-87-1
Molecular Formula:C10H13NO5S
Molecular Weight:259.283
Hs Code.:29225090
European Community (EC) Number:275-833-8,922-568-7,925-829-3
UNII:QE5K498QLP
DSSTox Substance ID:DTXSID80992277
Nikkaji Number:J299.032F
Wikidata:Q72436984
Mol file:71675-87-1.mol

Synonyms:71675-87-1;4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid;4-amino-5-ethylsulfonyl-2-methoxybenzoic acid;2-methoxy-4-amino-5-ethylsulfonylbenzoic acid;4-Amino-5-(ethylsulphonyl)-o-anisic acid;Benzoic acid, 4-amino-5-(ethylsulfonyl)-2-methoxy-;MFCD04973619;4-amino-5-(ethanesulfonyl)-2-methoxybenzoic acid;4-amino-5-(ethyl sulfonyl)-2-methoxybenzoic acid;EINECS 275-833-8;Amisulpride impurity (2-Methoxy-4-amino-5-ethylsulfonylbenzoic Acid);EC 275-833-8;4-Amino-5-(ethylsulphonyl)-2-methoxybenzoic Acid;2-Methoxy-4-amino-5-ethylsulfonyl benzoic acid;4-Amino-5-ethylsulfonyl-2-methoxybenzoicacid;4-Amino-5-(ethylsulfonyl)-2-methoxybenzoicacid;QE5K498QLP;SCHEMBL3313702;DTXSID80992277;OJVNCXHGGYYOPH-UHFFFAOYSA-N;AMY40446;BCP22957;CS-M1894;STK503889;AKOS005171595;AC-6121;CS-O-30835;GS-3369;s11440;SY042620;FT-0641361;2-methoxy-4-amino-5-ethylsulphonylbenzoic acid;2-methoxy-4-amino-5-ethysulfonyl benzoic acid;2-methoxy-4-amino-5-ethylsulphonyl benzoic acid;4-azanyl-5-ethylsulfonyl-2-methoxy-benzoic acid;4-amino-5-(ethylsulfonyl)-2-methoxy benzoic acid;A837283;A1-01727;W-104510

Suppliers and Price of 4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Methoxy-4-amino-5-ethylsulfonyl benzoic acid
100g
$ 460.00

TRC
2-Methoxy-4-amino-5-ethylsulfonylbenzoicAcid
100mg
$ 120.00

TRC
2-Methoxy-4-amino-5-ethylsulfonylbenzoicAcid
25mg
$ 65.00

TRC
2-Methoxy-4-amino-5-ethylsulfonylbenzoicAcid
250mg
$ 155.00

TCI Chemical
4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic Acid >98.0%(HPLC)(T)
5g
$ 158.00

TCI Chemical
4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic Acid >98.0%(HPLC)(T)
1g
$ 32.00

Medical Isotopes, Inc.
2-Methoxy-4-amino-5-ethylsulfonylbenzoicAcid
50 mg
$ 1840.00

Matrix Scientific
4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic acid
500mg
$ 95.00

Crysdot
4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic Acid 98%
100g
$ 248.00

ChemScene
4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic Acid 99.42%
25g
$ 84.00

Total 196 raw suppliers

Chemical Property of 4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic acid Edit

Chemical Property:

Appearance/Colour:Slightly pink solid
Vapor Pressure:4.78E-12mmHg at 25°C
Melting Point:82-85 °C
Refractive Index:1.568
Boiling Point:529.6 °C at 760 mmHg
PKA:4.09±0.10(Predicted)
Flash Point:274.1 °C
PSA：115.07000
Density:1.39 g/cm³
LogP:2.43120
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)
Water Solubility.:8.555g/L at 25℃
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:259.05144369
Heavy Atom Count:17
Complexity:375

Purity/Quality:

99%,99.5%, ^*data from raw suppliers

2-Methoxy-4-amino-5-ethylsulfonyl benzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCS(=O)(=O)C1=C(C=C(C(=C1)C(=O)O)OC)N
Uses An impurity found in amisulpride (A633250). Amisulpride EP Impurity E

Technology Process of 4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic acid

There total 7 articles about 4-Amino-5-(ethylsulfonyl)-2-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1119455-01-4
methyl 4-amino-5-(ethylthio)-2-methoxybenzoate

: 71675-87-1
2-methoxy-4-amino-5-ethylsulphonyl benzoic acid

Guidance literature:: methyl 4-amino-5-(ethylthio)-2-methoxybenzoate; With dihydrogen peroxide; sodium tungstate; In isopropyl alcohol; at 40 - 45 ℃; Industry scale;

With water; sodium hydroxide; In isopropyl alcohol; at 60 - 65 ℃; Industry scale;

With hydrogenchloride; In water; isopropyl alcohol; pH=4 - 4.5; Industry scale;

Reference yield: 80.0%

: 2-methoxy-4-amino-5-ethylthio benzoic acid

: 71675-87-1
2-methoxy-4-amino-5-ethylsulphonyl benzoic acid

Guidance literature:: With dihydrogen peroxide; sodium tungstate; In methanol; water; at 20 - 30 ℃; for 5h; Product distribution / selectivity;