4-Ethoxybutanoic acid methyl ester

Base Information

• Chemical Name: 4-Ethoxybutanoic acid methyl ester
• CAS No.: 29006-04-0
• Molecular Formula: C7H14O3
• Molecular Weight: 146.186
• Hs Code.: 2918990090
• Mol file: 29006-04-0.mol

Synonyms:4-Ethoxybutanoic acid methyl ester;Butyric acid,4-ethoxy-,methyl ester;Butanoic acid,4-ethoxy-,methyl ester;

Chemical Property of 4-Ethoxybutanoic acid methyl ester

Chemical Property:

• PSA: 35.53000
• LogP: 0.97610

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Ethoxybutanoic acid methyl ester

There total 2 articles about 4-Ethoxybutanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 4-ethoxybutan-1-ol (111-73-9) → 4-ethoxy-butyric acid methyl ester (29006-04-0)

Guidance literature:

Multistep reaction; (i) CrO₃, H₂SO₄, acetone, (ii) /BRN= 102415/;

DOI:10.1021/jo00812a017

Reference yield:

diethyl ether (60-29-7,927820-24-4) + methyl diazoacetate (6832-16-2) → Ethoxyessigsaeure-methylester (17640-26-5) + 4-ethoxy-butyric acid methyl ester (29006-04-0) + methyl-β-ethoxypropionate (101079-79-2)

Guidance literature:

Product distribution; Irradiation; with and without benzophenone, different temperatures, in liquid and solid phase;

DOI:10.1039/P29800000603

Reference yield: 61.0%

4-ethoxy-butyric acid methyl ester (29006-04-0) → 4-ethoxybutan-1-ol (111-73-9)

Guidance literature:

With sodium tetrahydroborate; sodium; In methanol; for 6h; Heating / reflux;

upstream raw materials:

diazomethane

4-ethoxybutan-1-ol

diethyl ether

methyl diazoacetate

Downstream raw materials:

4-ethoxybutan-1-ol