B-FLUORO-BENZENEETHANOL

Base Information

• Chemical Name: B-FLUORO-BENZENEETHANOL
• CAS No.: 2932-58-3
• Molecular Formula: C8H9FO
• Molecular Weight: 140.157
• Mol file: 2932-58-3.mol

Synonyms:2-Fluoro-2-phenylethanol;2-Fluoro-2-phenyl-ethanol;2-Fluor-2-phenylaethanol;2-Fluor-2-phenyl-aethanol;2-phenyl-2-fluoroethanol;

Chemical Property of B-FLUORO-BENZENEETHANOL

Chemical Property:

• PSA: 20.23000
• LogP: 1.68950

Purity/Quality:

99% ^*data from raw suppliers

b-fluoro-benzeneethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of B-FLUORO-BENZENEETHANOL

There total 8 articles about B-FLUORO-BENZENEETHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-acetoxy-1-fluoro-1-phenylethane (33315-78-5) → 2-fluoro-2-phenylethanol (2932-58-3)

Guidance literature:

With potassium hydroxide; In methanol; at 20 ℃; for 2h;

DOI:10.1002/(sici)1521-3897(200001)342:1<52::aid-prac52>3.0.co;2-h

Reference yield: 75.0%

styrene oxide (96-09-3) → 2-fluoro-2-phenylethanol (2932-58-3)

Guidance literature:

With iodine pentafluoride; triethylamine tris(hydrogen fluoride); In dichloromethane; at 20 ℃; for 5h;

DOI:10.1246/cl.2001.222

Reference yield: 74.0%

styrene oxide (96-09-3) + methanol (67-56-1) → 2-fluoro-2-phenylethanol (2932-58-3) + 2-methoxy-2-phenylethanol (2979-22-8)

Guidance literature:

With 3-ethyl-1-methylimidazolium hydrogen fluoride; In dichloromethane; at 20 ℃; for 12h; Further Variations:; Solvents; time; Product distribution;

DOI:10.1016/j.jfluchem.2005.09.016

upstream raw materials:

styrene oxide

2-acetoxy-1-fluoro-1-phenylethane

methanol

(2-bromo-1-fluoroethyl)benzene

Downstream raw materials:

(2-chloro-1-fluoroethyl)benzene

(2-bromo-1-fluoroethyl)benzene

d'acide 2-fluoro-2-phenyl acetique

2-fluoro-2-phenylethyl-4-methylbenzene sulphonate